Evidence map›Paper›PMID 42245919›Full record

ArticleRSC chemical biology2026

The position of hydrophobic residues impacts cellular uptake and intracellular localization of cell penetrating peptides.

Adeline Schmitt, Helma Wennemers

Abstract read
In one paragraph

Article in RSC chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adeline SchmittLaboratory of Organic Chemistry, ETH Zürich, D-CHAB Vladimir-Prelog-Weg 3 Zürich 8093 Switzerland helma.wennemers@org.chem.ethz.ch.ORCID https://orcid.org/0000-0003-2182-532X
Helma WennemersLaboratory of Organic Chemistry, ETH Zürich, D-CHAB Vladimir-Prelog-Weg 3 Zürich 8093 Switzerland helma.wennemers@org.chem.ethz.ch.ORCID https://orcid.org/0000-0002-3075-5741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-penetrating peptides (CPPs) are widely used to deliver cargo into mammalian cells, yet efficient cellular uptake and endosomal escape remain key challenges. In this study, we evaluated how hydrophobic (4

Identifiers

PMID42245919
PMCPMC13232632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.