Evidence map›Paper›PMID 42245879›Full record

ArticleCureus2026

Chronic Iron Deficiency Anemia as the Initial Manifestation of Undiagnosed Von Willebrand Disease in a Woman With Long-Standing Menorrhagia: A Case Report.

Shamas Rafique, Iqra Rafiq

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shamas RafiqueInternal Medicine, BeeWell International Hospital, Islamabad, PAK.
Iqra RafiqGeneral Medicine, Services Hospital Lahore, Lahore, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron deficiency anemia is a common clinical condition in reproductive‑age women and is frequently attributed to gynecologic blood loss. However, underlying inherited bleeding disorders remain underrecognized contributors. We present a case of a woman with chronic fatigue, weakness, and long-standing menorrhagia who was repeatedly treated for iron deficiency anemia without sustained improvement. Subsequent hematologic evaluation revealed Von Willebrand factor (VWF) deficiency consistent with Von Willebrand disease. This case highlights the importance of recognizing abnormal uterine bleeding as a potential manifestation of an underlying hemostatic disorder and underscores the need for early diagnostic evaluation to prevent prolonged morbidity and avoid delays in definitive management.

Indexed as

abnormal uterine bleedingbleeding disorderscoagulation disordersheavy menstrual bleedinghematologyiron deficiency anemiamenorrhagiavon willebrand diseasevwf deficiencywomen’s health

Identifiers

PMID42245879
PMCPMC13232889

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.