Evidence map›Paper›PMID 42245864›Full record

ArticleCureus2026

Twice-Daily Scrambler Therapy for a Patient With Spinocerebellar Ataxia Suffering From Refractory Neuropathic Back Pain: A Case Report.

Pak Hei Tristan Chan, Ka Lai Chu

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pak Hei Tristan ChanDepartment of Anesthesiology, Pain Medicine, and Operating Services, United Christian Hospital, Kwun Tong, HKG.
Ka Lai ChuDepartment of Anesthesiology, Pain Medicine, and Operating Services, United Christian Hospital, Kwun Tong, HKG.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinocerebellar ataxia (SCA) is a group of progressive neurodegenerative diseases. These patients often suffer from pain with multiple etiologies. Our patient suffers from distressing neuropathic back pain, which was only marginally alleviated with high-dose conventional antineuropathic agents while suffering from the side effects. A course of scrambler therapy was prescribed, and sustained relief of neuropathic back pain was achieved for at least eight weeks after completion of scrambler therapy. This is the first case of neuropathic pain in SCA to be treated with scrambler therapy, to the best of our knowledge. Compared with usual daily scrambler therapy sessions, our patient received twice-daily sessions. The main takeaways from our case are that 1) scrambler therapy is a potential treatment for neuropathic pain in SCA patients; 2) it can treat neuropathic pain refractory to conventional antineuropathic agents with the added benefit of reducing the requirement as well as side effects associated with conventional antineuropathic agents; and 3) twice-daily sessions are a potential alternative to standard daily sessions with positive logistical implications.

Indexed as

case reportneuropathic painsca3scrambler therapyspinocerebellar ataxiatype 3

Identifiers

PMID42245864
PMCPMC13231830

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.