Evidence map›Paper›PMID 42245820›Full record

ArticleEpilepsy currents2026

Hippocampal Long Axis Differentiation in Memory and Seizure Networks.

Kathryn McClain, Quynh-Anh Nguyen, Leigh Sepeta, Ivan Soltesz, Anli Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsy currents, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kathryn McClainCenter for Neural Science and Department of Physics, New York University, New York, NY, USA.ORCID https://orcid.org/0000-0002-3597-9963
Quynh-Anh NguyenDepartment of Pharmacology and the Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.ORCID https://orcid.org/0000-0003-4910-7899
Leigh SepetaCenter for Neuroscience Research and Department of Neuropsychology, Children's National Hospital, The George Washington University School of Medicine, Washington, DC, USA.
Ivan SolteszDepartment of Neurosurgery, Stanford University, Stanford, CA, USA.ORCID https://orcid.org/0000-0003-1493-3744
Anli LiuDepartment of Neurology, NYU Grossman School of Medicine, NYU Neuroscience Institute, New York, NY, USA.ORCID https://orcid.org/0000-0002-1118-981X

Funding

Hippocampal-Neocortical Interactions During Naturalistic LearningR01NS127954 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Anli A Liu · 2023 to 2026
$2.5M
Human hippocampal oscillations during visuomotor explorationR61DC022830 · NIDCD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GYORGY BUZSAKI, Anli A Liu · 2025 to 2026
$2.0M
NIDCD NIH HHS R61 DC022830NINDS NIH HHS R01 NS127954
6 · The paper itself

Abstract

The structure-function gradient along the hippocampal long axis is recognized but poorly understood. Rodent recordings mainly sample the dorsal hippocampus (posterior), while surgical recordings in epilepsy patients typically sample from the ventral hippocampus (anterior), because of greater known involvement in seizure networks. These divergent recording practices imply that the mechanisms of rodent spatial navigation may not directly apply to human episodic memory. In general, the role of the posterior hippocampus in human memory and seizure networks is under-appreciated. We survey the basic, translational, and clinical research accounting for long-axis differentiation and outline future research directions.

Indexed as

hippocampuslong axismemoryspatial navigationthetatranslational neuroscience

Identifiers

PMID42245820
PMCPMC13229910

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.