Evidence map›Paper›PMID 42245784›Full record

ArticleResearch square2026

Geriatric syndromes, multimorbidity, and life satisfaction among older adults in India: a cross-sectional analysis of the Longitudinal Ageing Study in India (LASI).

Bhrigu Jain, Akash Jaiswal, Mujtaba Waris, Jeetendra Yadav, Pramod Kumar, Prasun Chatterjee

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In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Bhrigu JainMedanta The Medicity.
Akash JaiswalFortis Memorial Research Institute.
Mujtaba WarisUniversity Hospitals Sussex NHS Foundation Trust.
Jeetendra YadavIndian Council of Medical Research.
Pramod KumarAll India Institute of Medical Sciences.
Prasun ChatterjeeIndraprastha Apollo Hospitals.

Funding

Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
The Longitudinal Aging Study in IndiaR01AG042778 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI AROKIASAMY, PERIANAYAGAM, BLOOM, DAVID E · 2013 to 2019
$9.0M
NIA NIH HHS R01 AG042778NIA NIH HHS R01 AG051125
6 · The paper itself

Abstract

Background: Older adults in low- and middle-income countries are increasingly affected by both chronic-disease multimorbidity (MM) and geriatric syndromes (GS), but evidence on their joint impact on subjective well-being from the Indian subcontinent is limited. We examined the prevalence of MM and GS, and quantified their independent and joint associations with life satisfaction, in a nationally representative sample of older Indians. Methods: We conducted a cross-sectional analysis of Wave 1 of the Longitudinal Ageing Study in India (LASI, 2017-18), restricted to community-dwelling adults aged 60 years or older (n = 30,811 with complete data on key variables; weighted mean age 68.6 years, SD 7.3). Multimorbidity was defined as two or more of nine self-reported physician-diagnosed chronic conditions. Geriatric syndromes were defined as the presence of at least one of seven syndromes: cognitive impairment (general cognitive factor score below the 10th weighted percentile), hearing impairment, vision impairment (poor self-rated near or distance vision), falls in the past 2 years, urinary incontinence, depression (Center for Epidemiologic Studies Depression-10 score ≥ 4 symptoms), and underweight (body-mass index < 18.5 kg/m Results: The weighted prevalence of MM was 23.4 % and of any GS 70.5 %. State-level MM prevalence ranged from 4.1 % in Arunachal Pradesh to 55.7 % in Kerala. After full adjustment, the presence of any GS was associated with a 2.36-point lower life satisfaction score (95 % CI - 2.61 to - 2.11; p < 0.001), with a clear dose-response by GS count (1 GS: β = - 1.52; 2 GS: β = - 2.89; ≥ 3 GS: β = - 4.33; all p < 0.001). In contrast, MM was not independently associated with life satisfaction in the adjusted model (β = + 0.08; 95 % CI - 0.33 to + 0.49; p = 0.71), nor was the MM × GS interaction term (β = - 0.19; 95 % CI - 0.69 to + 0.30; p = 0.44). Higher education, greater wealth, co-residence with family, urban residence, and female sex were independently associated with higher life satisfaction. Findings were robust to a sensitivity analysis excluding depression from the GS composite (GS β = - 1.48; 95 % CI - 1.72 to - 1.23). Conclusions: In community-dwelling older Indians, geriatric syndromes, not multimorbidity are the principal correlate of reduced life satisfaction, with a graded dose-response by number of syndromes. Primary-care programmes for older adults in India, including the National Programme for Health Care of the Elderly and the Ayushman Bharat Health and Wellness Centres, should prioritise structured screening and management of geriatric syndromes alongside chronic-disease care, particularly in rural and lower-wealth populations where GS prevalence is highest but specialist access is most limited. Trial registration: Not applicable. This study is a secondary analysis of observational survey data and did not involve a health-care intervention.

Indexed as

AgedGeriatric AssessmentGeriatric SyndromesHealth SurveysIndiaLASIMultimorbidityPersonal Satisfaction

Identifiers

PMID42245784
PMCPMC13232450

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.