Evidence map›Paper›PMID 42245656›Full record

ArticleFrontiers in immunology2026

Respiratory chain gene mutations associated with global phylogenetic clustering of drug-resistant

Qiang Ji, Yawei Hou, Yameng Li

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qiang JiShandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Yawei HouDepartment of Traditional Chinese Medicine, Qilu Second Hospital of Shandong University, Jinan, Shandong, China.
Yameng LiDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Shandong First Medical University (Affiliated Hospital of Shandong Academy of Medical Sciences), Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The regulatory mechanism of respiratory chain in Objective: To elucidated the effect of gene mutations in the respiratory chain on MDR isolates. Methods: Whole-genome sequencing was performed on analyzed strains of Results: Overall, a total of 13402 isolates of Conclusion: Our study proposed that SNPs in genes of the respiratory chain were related to the phylogenetic clustering and development of MDR isolates, which provides new insights for preventing the phylogenetic clustering and development of MDR isolates. These insights provide valuable information for the development of potential therapeutic targets for MDR isolates.

Indexed as

Bacterial ProteinsDrug Resistance, Multiple, BacterialMutationMycobacterium tuberculosisTuberculosis, Multidrug-ResistantGenome, BacterialHumansPhylogenyPolymorphism, Single NucleotideWhole Genome SequencingBacterial Proteinsmultidrug-resistantMycobacterium tuberculosisrespiratory chaintransmissionwhole-genome sequencing

Identifiers

PMID42245656
PMCPMC13229807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.