Evidence map›Paper›PMID 42245652›Full record

ArticleFrontiers in immunology2026

Annotation of bat IG H/L/K loci and analysis of the characteristics of bat BCR-CDR3 repertoires.

QinLu Liu, Long Ma, Jun Li, LongYu Liu, Hao Zhou, ZeGang Liu, HuiFang Wang, XinSheng Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

QinLu LiuDepartment of Immunology, Zunyi Medical University, Guizhou Provincial Research Center for Applied Immunomolecular Engineering, Guizhou Provincial Innovation Base for Graduate Education in Immunology, Guizhou Provincial Key Discipline of Immunology, Zunyi, China.
Long MaDepartment of Immunology, Zunyi Medical University, Guizhou Provincial Research Center for Applied Immunomolecular Engineering, Guizhou Provincial Innovation Base for Graduate Education in Immunology, Guizhou Provincial Key Discipline of Immunology, Zunyi, China.
Jun LiDepartment of Immunology, Zunyi Medical University, Guizhou Provincial Research Center for Applied Immunomolecular Engineering, Guizhou Provincial Innovation Base for Graduate Education in Immunology, Guizhou Provincial Key Discipline of Immunology, Zunyi, China.
LongYu LiuDepartment of Immunology, Zunyi Medical University, Guizhou Provincial Research Center for Applied Immunomolecular Engineering, Guizhou Provincial Innovation Base for Graduate Education in Immunology, Guizhou Provincial Key Discipline of Immunology, Zunyi, China.
Hao ZhouDepartment of Immunology, Zunyi Medical University, Guizhou Provincial Research Center for Applied Immunomolecular Engineering, Guizhou Provincial Innovation Base for Graduate Education in Immunology, Guizhou Provincial Key Discipline of Immunology, Zunyi, China.
ZeGang LiuDepartment of Immunology, Zunyi Medical University, Guizhou Provincial Research Center for Applied Immunomolecular Engineering, Guizhou Provincial Innovation Base for Graduate Education in Immunology, Guizhou Provincial Key Discipline of Immunology, Zunyi, China.
HuiFang WangDepartment of Immunology, Zunyi Medical University, Guizhou Provincial Research Center for Applied Immunomolecular Engineering, Guizhou Provincial Innovation Base for Graduate Education in Immunology, Guizhou Provincial Key Discipline of Immunology, Zunyi, China.
XinSheng YaoDepartment of Immunology, Zunyi Medical University, Guizhou Provincial Research Center for Applied Immunomolecular Engineering, Guizhou Provincial Innovation Base for Graduate Education in Immunology, Guizhou Provincial Key Discipline of Immunology, Zunyi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bats represent the second largest order of mammals and are the only flying mammals, exhibiting remarkable biological characteristics such as viral tolerance, longevity, and low tumor incidence. Although bats serve as reservoirs for numerous zoonotic viruses, they remain asymptomatic without overt infection. However, the mechanisms and effects of B-cell adaptive immune responses in bats are largely unknown. In mammals, BCR V(D)J gene recombination and the formation of the CDR3 repertoire are key mechanisms underlying B-cell diversity, specificity, and memory responses. In this study, we performed, for the first time, a chromosome-level annotation of the IGK locus (17 KV; 4 KJ;1 LC) and IGL locus (74 LV; 6 LJ-LC gene clusters) in

Indexed as

ChiropteraComplementarity Determining RegionsImmunoglobulin Heavy ChainsImmunoglobulin Light ChainsReceptors, Antigen, B-CellAnimalsB-LymphocytesEvolution, MolecularMolecular Sequence AnnotationPhylogenyComplementarity Determining RegionsImmunoglobulin Heavy ChainsImmunoglobulin Light ChainsReceptors, Antigen, B-CellAntrozous pallidusBCR CDR3 repertoirehigh-throughput sequencingIG locus annotationRhinolophus ferrumequinum

Identifiers

PMID42245652
PMCPMC13229784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.