Evidence map›Paper›PMID 42245546›Full record

Trial reportFrontiers in nutrition2026

Resistant dextrin promotes beneficial fecal bacteria in high and low fiber diet populations: a randomized, double-blinded, controlled pilot study.

Caroline Perreau, Diego Tomassi, Odile Capronnier, Thomas Carton, Clémentine Thabuis, Laetitia Guérin-Deremaux

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05105425 (The Effects of Daily Supplementation of Nutriose® on the Fecal Microbiota in Volunteers Over 4 Weeks), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05105425 nacompletednot on this map

The Effects of Daily Supplementation of Nutriose® on the Fecal Microbiota in Volunteers Over 4 Weeks: a Randomized, Double-blinded, Placebo Conrolled Pilot Study.

TypeinterventionalSponsorRoquette FreresRan2021 to 2023Enrolled124ConditionsHealthy Male VolunteersArmsNUTRIOSE®, GLUCIDEX® IT21 (Placebo)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caroline PerreauROQUETTE, Life Sciences R&D, Lestrem, France.
Diego TomassiBIOFORTIS SAS, Saint-Herblain, France.
Odile CapronnierBIOFORTIS SAS, Saint-Herblain, France.
Thomas CartonBIOFORTIS SAS, Saint-Herblain, France.
Clémentine ThabuisROQUETTE, Life Sciences R&D, Lestrem, France.
Laetitia Guérin-DeremauxROQUETTE, Life Sciences R&D, Lestrem, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: The average intake of dietary fibers known to beneficially modulate the gut microbiota is below recommendations in high-income countries. This study aimed to evaluate the gut effects of resistant dextrin in healthy male adults with normal weight, consuming high (≥ 25 g/day; HF) or low (≤15 g/day; LF) levels of fiber as part of their usual diet. Methods: In this randomized, double-blind, placebo-controlled trial, participants received either 15 g/day of resistant dextrin (NUTRIOSE Results: Overall, 124 subjects were recruited, 62 in each treatment arm; 57 in HF, 67 in LF; age: 36.2 ± 11.6 years. The mean relative abundance of Conclusion: The tested resistant dextrin was effective in modulating the gut microbiota after four weeks of supplementation in healthy male volunteers, favoring the Clinical trial registration: https://clinicaltrials.gov/, identifier NCT05105425.

Indexed as

fibergut microbiotaParabacteroidesprebioticresistant dextrin

Identifiers

PMID42245546
PMCPMC13232062

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.