Evidence map›Paper›PMID 42245472›Full record

ArticleJCEM case reports2026

Adrenal insufficiency influences the pattern of thyrotoxicosis toward triiodothyronine predominance.

Azusa Maruoka, Kumiko Nishimura, Chika Mukai, Kazuhisa Takahashi, Junichiro Irie, Nagaoki Toyoda

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Azusa MaruokaInternal Medicine II, Kansai Medical University, 2-5-1, Shinmachi, Hirakata-City, Osaka 573-1010, Japan.
Kumiko NishimuraInternal Medicine II, Kansai Medical University, 2-5-1, Shinmachi, Hirakata-City, Osaka 573-1010, Japan.
Chika MukaiInternal Medicine II, Kansai Medical University, 2-5-1, Shinmachi, Hirakata-City, Osaka 573-1010, Japan.
Kazuhisa TakahashiInternal Medicine II, Kansai Medical University, 2-5-1, Shinmachi, Hirakata-City, Osaka 573-1010, Japan.
Junichiro IrieInternal Medicine II, Kansai Medical University, 2-5-1, Shinmachi, Hirakata-City, Osaka 573-1010, Japan.
Nagaoki ToyodaInternal Medicine II, Kansai Medical University, 2-5-1, Shinmachi, Hirakata-City, Osaka 573-1010, Japan.ORCID https://orcid.org/0000-0003-3487-0306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum-free thyroxine (FT4) levels are typically higher than free triiodothyronine (FT3) levels at the onset of thyrotoxicosis in patients with painless thyroiditis, reflecting the high ratio of stored thyroid hormone in the thyroid gland. We report a case of a 58-year-old man with painless thyroiditis and adrenal insufficiency caused by isolated adrenocorticotropin (ACTH) deficiency (IAD). Upon admission, the FT3 level was high, while the FT4 level was within the normal range. Likewise, the FT3/FT4 ratio was high. Therefore, the diagnosis of triiodothyronine (T3) thyrotoxicosis was made. He was diagnosed with painless thyroiditis because he did not have neck pain, and

Indexed as

isolated ACTH deficiencypainless thyroiditisT3 thyrotoxicosis

Identifiers

PMID42245472
PMCPMC13231169

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.