Evidence map›Paper›PMID 42245340›Full record

ArticleFrontiers in public health2026

Differential risk profiles for geriatric depression, anxiety, and sleep disturbances in rural China: insights from the Taierzhuang cohort.

Renfeng Zhang, Qian Yu, Yunshan Wang, Xiaoyi Zhao, Shuyi Yu, Zhongyu Dong, Jinghai Hou, Xingguo Qin, Ming Li, Mo Wang

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Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Renfeng ZhangDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Qian YuDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Yunshan WangDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Xiaoyi ZhaoDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Shuyi YuDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Zhongyu DongPeople's Hospital of Taierzhuang District, Zaozhuang City, Zaozhuang, China.
Jinghai HouPeople's Hospital of Taierzhuang District, Zaozhuang City, Zaozhuang, China.
Xingguo QinPeople's Hospital of Taierzhuang District, Zaozhuang City, Zaozhuang, China.
Ming LiDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Mo WangDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mental health disorders among older adults in rural China present substantial public health challenges, yet their differential risk factors and practical screening tools remain understudied. Methods: We analyzed data from 4,180 participants in the Taierzhuang Aging Cohort. Using multivariate logistic regression, we identified independent risk factors for depression, anxiety, and insomnia. Predictor variables were confirmed to be sufficiently independent by evaluating bivariate correlations, variance inflation factors, and linearity in the logit. Corresponding nomograms were developed for risk prediction. Results: The prevalence of anxiety symptoms, depressive symptoms, and insomnia was 22.1%, 22.7%, and 29.5%, respectively. Multivariate analysis revealed distinct risk profiles for each condition: the absence of a chronic disease (OR: 1.57; 95% CI: 1.28-1.94) and older age were independent predictors of depressive symptoms; while a poor spousal relationship (OR: 1.55; 95% CI: 1.11-2.16) was a risk factor for anxiety symptoms, while physical activity 1-2 times/week (vs. ≥3 times/week: OR = 0.69; 95% CI: 0.53-0.90) was associated with decreased risk; inconstrast, female gender (OR: 1.33; 95% CI: 1.06-1.67) and lower exercise frequency were significantly associated with insomnia. Based on these findings, we developed three clinical prediction nomograms that integrate these independent predictors to facilitate individualized risk assessment. Conclusion: This study establishes distinct risk profiles for common mental health conditions in rural Chinese older adults and provides practical nomograms for risk assessment in primary care settings, facilitating targeted prevention strategies for these under-served populations.

Indexed as

AnxietyDepressionRural PopulationSleep Wake DisordersAgedAged, 80 and overChinaCohort StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsSleep Initiation and Maintenance Disordersanxietycohortdepressiongeriatric mental healthpublic health

Identifiers

PMID42245340
PMCPMC13229768

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