Differences in food sensitization patterns between infants/toddlers and children: a cross-sectional study of patients aged 0-14 years in urban China.

Huimin Huang, Haisheng Hu, Linshu Xu, Yanting Fang, Yinghong Lin, Na Li, Baoqing Sun

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Article in Frontiers in allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Huimin Huang *Department of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Haisheng Hu *Department of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Linshu XuDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Yanting FangDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Yinghong LinDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Na LiChildren's Neurorehabilitation Laboratory, Shenyang Children's Hospital, Shenyang, China.

Baoqing SunDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: With rapid urbanization in China, the prevalence of food allergies among children has significantly increased. To explore the evolution of sensitization patterns in early life, this study aimed to systematically compare allergen profiles among infants/toddlers and children with food sensitization to provide evidence-based support for implementation. Method: This study analyzed sensitization to 7 common food allergens in 947 patients aged 0-14 years (402 children aged 4-14 years and 545 infants/toddlers aged 0-3 years) with food sensitization in urban of China. Results: In children, spring and autumn visits were the more common (all at 26.4%), and the highest sensitization rate was egg whites (49.0%), followed by hazelnuts (43.8%), and milk (32.6%). In infants/toddlers, winter visits were the most common (28.3%), and the highest sensitization rate was egg white (75.4%), followed by milk (55.4%) and wheat (15.2%). Meanwhile, the positive rates for egg whites (75.4% vs. 49.0%, Conclusion: Children of different ages showed distinct sensitization characteristics, and the sensitization pattern of children may have developed from that of infancy. These findings support the adoption of differentiated allergy risk management and prevention strategies at different life stages.

Indexed as

allergenchildhood allergiesepidemiologyfood sensitizationsIgE

Identifiers

PMID42245188

DOI10.3389/falgy.2026.1802814

PMCPMC13230059

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