ArticleFrontiers in pediatrics2026
Implementation of a Golden Hour protocol for initial management of preterm infants: a quality improvement study.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study implemented and evaluated a systematic approach for managing preterm infants <31 weeks of gestational age (wGA) and/or estimated fetal weight (EFW)<1300 g during their first hour of life. The primary focus was organizational efficiency, thermal regulation, and hypoglycemia prevention, with secondary assessment of clinical outcomes and team perception. Methods: A prospective observational study was conducted from January 2022 to July 2023 in a tertiary neonatal intensive care unit (NICU). Infants meeting inclusion criteria were compared with a retrospective 2019 control cohort. The Golden Hour (GH) protocol emphasized anticipation, role assignment, and early interventions, including umbilical venous catheterization (UVC), and parenteral nutrition (PN) initiation. Outcomes included procedural metrics (e.g., time to incubator closure, UVC placement) and clinical outcomes (e.g., hypothermia, hypoglycemia, mortality, and major comorbidities of prematurity). Team perception was assessed via survey. Results: 77 infants were included in the GH group and 72 infants in a retrospective control group. GH infants experienced less hypothermia (23/77 vs. 36/72 - Conclusion: The GH protocol improved thermal regulation and team efficiency without altering clinical outcomes. Its positive effect on teamwork supports further evaluation in larger studies.
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