Evidence map›Paper›PMID 42245090›Full record

ArticlePublic health weekly report2026

Severe Acute Respiratory Syndrome Coronavirus 2 Detection and Variant Analysis in Respiratory Specimens from a Clinical Laboratory.

Jin Sun No, Chaeyoung Lee, Dongju Kim, Ji Yeong Noh, Min Jin Kim, In Tae Kim, Il-Hwan Kim, Eun-Jin Kim

Abstract read
In one paragraph

Article in Public health weekly report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jin Sun NoDivision of Emerging Infectious Diseases, Department of Laboratory Diagnosis and analysis, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0003-4400-7872
Chaeyoung LeeDivision of Emerging Infectious Diseases, Department of Laboratory Diagnosis and analysis, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0002-0969-039X
Dongju KimDivision of Emerging Infectious Diseases, Department of Laboratory Diagnosis and analysis, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0003-2873-9475
Ji Yeong NohDivision of Emerging Infectious Diseases, Department of Laboratory Diagnosis and analysis, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0002-2302-9012
Min Jin KimDepartment of Laboratory Medicine, Seegene Medical Foundation, Seoul, Korea.ORCID https://orcid.org/0000-0003-1645-6101
In Tae KimR&D Business Division, Seegene Medical Foundation, Seoul, Korea.ORCID https://orcid.org/0000-0002-2322-3018
Il-Hwan KimDivision of Emerging Infectious Diseases, Department of Laboratory Diagnosis and analysis, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0003-3566-5523
Eun-Jin KimDivision of Emerging Infectious Diseases, Department of Laboratory Diagnosis and analysis, Korea Disease Control and Prevention Agency, Cheongju, Korea.ORCID https://orcid.org/0000-0001-6784-8004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The Korea Respiratory Virus Integrated Surveillance System (K-RISS) operates as a sentinel surveillance system. This study complements K-RISS by testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients who presented to healthcare facilities with respiratory symptoms but were not tested for coronavirus disease 2019 (COVID-19). Methods: Among specimens collected from patients presenting to healthcare facilities with respiratory symptoms and submitted for multiplex testing for 19 respiratory viruses, specimens that tested negative for all respiratory viruses were additionally tested for SARS-CoV-2 using molecular assays. Whole-genome sequencing using next-generation sequencing was performed on SARS-CoV-2-positive specimens to characterize circulating sublineages. Results: Of the 5,400 total specimens, 591 were SARS-CoV-2-positive, resulting in an overall positivity rate of 10.9%. This positivity rate exhibited a seasonal pattern: it increased after July, peaked in August, and subsequently declined. This trend aligned with the annual SARS-CoV-2 detection rates observed by K-RISS. Moreover, changes in variant prevalence identified through whole-genome sequencing were comparable to those reported by K-RISS. Conclusions: This study's approach of testing and analyzing respiratory virus-negative specimens after Korea transitioned to the current sentinel surveillance system identified additional SARS-CoV-2-positive specimens. This enabled a reliable assessment of domestic COVID-19 transmission and variant circulation occurring during the surveillance transition period. It also confirmed that the current K-RISS delivers representative insights into community-level epidemic trends.

Indexed as

COVID-19Korea Respiratory Virus Integrated Surveillance SystemRespiratory virusSARS-CoV-2

Identifiers

PMID42245090
PMCPMC13232934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.