Evidence map›Paper›PMID 42244959›Full record

ReviewNeuroscience applied2026

Linking inflammatory and structural neuroimaging biomarkers in treatment-resistant depression: Current evidence and emerging hypotheses.

Simge Seren Kirlioglu Balcioglu, Marco Paolini, Bernhard T Baune, Igor Branchi, Annamaria Cattaneo, Marion Leboyer, Benedetta Vai, Livia De Picker

Abstract readReview
In one paragraph

Review in Neuroscience applied, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Simge Seren Kirlioglu BalciogluDepartment of Psychiatry, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkiye.
Marco PaoliniPsychiatry and Clinical Psychobiology Unit, Division of Neuroscience, IRCCS Ospedale San Raffaele, Milan, Italy.
Bernhard T BauneDepartment of Psychiatry, University of Münster, Münster, Germany.
Igor BranchiCenter for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy.
Annamaria CattaneoBiological Psychiatric Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
Marion LeboyerFondation FondaMental, Créteil, France.
Benedetta VaiPsychiatry and Clinical Psychobiology Unit, Division of Neuroscience, IRCCS Ospedale San Raffaele, Milan, Italy.
Livia De PickerUniversity Psychiatric Hospital Campus Duffel, Duffel, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•TRD is associated with immune alterations across peripheral and central domains.•TRD may show hippocampal and white matter changes that may be linked to immune-related processes.•Integrating immune and neuroimaging findings may contribute to biologically informed stratification of treatment-resistant depression.

Identifiers

PMID42244959
PMCPMC13231077

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.