Evidence map›Paper›PMID 42244938›Full record

ArticleNature and science of sleep2026

Uncontrolled Hypertension from Inappropriate Ventilator Settings in Obstructive Sleep Apnea: A Case Report.

Si-Rui Tian, Robert Joseph Thomas, Yue-Nan Ni

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature and science of sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Si-Rui TianDepartment of Respiratory, Critical Care and Sleep Medicine, West China School of Medicine and West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China.
Robert Joseph ThomasDivision of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Yue-Nan NiDepartment of Respiratory, Critical Care and Sleep Medicine, West China School of Medicine and West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report explores a typical instance of poorly controlled secondary hypertension associated with obstructive sleep apnea (OSA), specifically exacerbated during bilevel positive airway pressure (PAP) therapy, which was an inappropriate ventilator mode. The patient exhibited uncontrolled blood pressure and a high residual apnea-hypopnea index (AHI) while on bilevel therapy. Following a guided retitration of PAP therapy, both blood pressure control and residual AHI improved substantially. This report aims to provide an in-depth analysis of pathophysiological mechanisms underlying PAP therapy interactions with hypertension in OSA patients and to summarize key points for ventilator management in clinical practice.

Indexed as

bilevelcase reportcentral sleep apneahypertensionobstructive sleep apneapositive airway pressure

Identifiers

PMID42244938
PMCPMC13232533

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.