ArticleFrontiers in urology2026
Case Report: Low-frequency tibial nerve stimulation: demonstrating a novel therapeutic option for Fowler's syndrome through a pilot case series.
Article in Frontiers in urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Fowler's Syndrome is a critically under-researched area of Women's Urological health. The condition, which causes severe urinary retention in the absence of any obvious obstructive pathology, lacks any non-invasive options for treatment. Transcutaneous Tibial Nerve Stimulation (TTNS) is an established treatment strategy for disorders of incontinence that is non-invasive, safe, and efficacious. Computer based modelling and preliminary animal experimentation indicates that ultra-low frequency TTNS (1-2 Hz) may induce an excitatory effect on bladder function that is of particular therapeutic relevance to Fowler's Syndrome. Therefore, the present case series describes a three-armed randomised-control (crossover) pilot study conducted from a biomechanical perspective in a population suffering from Fowler's Syndrome. The study aimed to address the question of if the novel application of low-frequency TTNS could ameliorate the symptoms of Fowler's Syndrome. Patients (
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