Evidence map›Paper›PMID 42244823›Full record

ArticleEuropean journal of anaesthesiology and intensive care2026

The diaphragm-sparing effect of interscalene block with a low-volume of ropivacaine 0.1% vs. 0.5%: A double-blind, controlled, randomised trial.

Anne-Laure Verbeke, Antoine Jeanneteau, Julie Bellet, Michael Genin, Cedric Cirenei, Arnaud Alluin, Benoit Tavernier

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of anaesthesiology and intensive care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04173364 (Interscalene Block and Dysfunction Diaphragmatic), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04173364 phase3completednot on this map

Interscalene Block and Dysfunction Diaphragmatic: Effect of Low Volume of Ropivacaine 0,1%. A Randomised, Controlled Trial

TypeinterventionalSponsorUniversity Hospital, LilleRan2019 to 2020Enrolled60ConditionsDiaphragmatic ParalysisArmsRopivacaine 0.5% Injectable Solution, Ropivacaine 0.1% Injectable Solution
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne-Laure VerbekeFrom the CHU Lille, Pôle d'anesthésie-réanimation, and University Lille, CHU Lille, ULR 2694, METRICS: Évaluation des Technologies de santé et des Pratiques médicales, Lille, France (ALV, AJ, JB, MG, CC, AA, BT).
Antoine JeanneteauFrom the CHU Lille, Pôle d'anesthésie-réanimation, and University Lille, CHU Lille, ULR 2694, METRICS: Évaluation des Technologies de santé et des Pratiques médicales, Lille, France (ALV, AJ, JB, MG, CC, AA, BT).
Julie BelletFrom the CHU Lille, Pôle d'anesthésie-réanimation, and University Lille, CHU Lille, ULR 2694, METRICS: Évaluation des Technologies de santé et des Pratiques médicales, Lille, France (ALV, AJ, JB, MG, CC, AA, BT).
Michael GeninFrom the CHU Lille, Pôle d'anesthésie-réanimation, and University Lille, CHU Lille, ULR 2694, METRICS: Évaluation des Technologies de santé et des Pratiques médicales, Lille, France (ALV, AJ, JB, MG, CC, AA, BT).
Cedric CireneiFrom the CHU Lille, Pôle d'anesthésie-réanimation, and University Lille, CHU Lille, ULR 2694, METRICS: Évaluation des Technologies de santé et des Pratiques médicales, Lille, France (ALV, AJ, JB, MG, CC, AA, BT).
Arnaud AlluinFrom the CHU Lille, Pôle d'anesthésie-réanimation, and University Lille, CHU Lille, ULR 2694, METRICS: Évaluation des Technologies de santé et des Pratiques médicales, Lille, France (ALV, AJ, JB, MG, CC, AA, BT).
Benoit TavernierFrom the CHU Lille, Pôle d'anesthésie-réanimation, and University Lille, CHU Lille, ULR 2694, METRICS: Évaluation des Technologies de santé et des Pratiques médicales, Lille, France (ALV, AJ, JB, MG, CC, AA, BT).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite improvements, the incidence of hemidiaphragmatic paralysis following interscalene brachial plexus block (ISB) is still significant at 20-40%.

objectivesWe tested the hypothesis whereby the use of a low volume of ropivacaine 0.1% reduces the incidence of hemidiaphragmatic dysfunction (compared with the same volume of ropivacaine 0.5%), while providing sufficient analgesia following arthroscopic shoulder surgery.

designRandomised controlled trial.

settingA tertiary university hospital. PATIENTS: Sixty patients undergoing shoulder arthroscopy under general anaesthesia.

interventionUltrasound-guided ISB with 7 ml of ropivacaine 0.1% or ropivacaine 0.5%.

main outcome measuresThe primary outcome was the incidence of hemidiaphragmatic dysfunction (a decrease in diaphragm excursion >25% of baseline) 30 min after ISB. The secondary outcomes included hemidiaphragmatic paralysis (a decrease in diaphragm excursion >75% of baseline), spirometry variables and postoperative analgesia.

resultsHemidiaphragmatic dysfunction occurred in 7/30 (23%) patients in the experimental group and in 29/30 (97%) patients in the control group,

conclusionsISB with 7 ml of ropivacaine 0.1% is associated with a lower incidence of hemidiaphragmatic dysfunction, when compared with the same volume of ropivacaine 0.5%, but at the cost of potentially less effective postoperative analgesia.

trial registrationhttps://clinicaltrials.gov/ct2/show/NCT04173364.

Identifiers

PMID42244823
PMCPMC13232923

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.