Evidence map›Paper›PMID 42244807›Full record

ArticleEvolution letters2026

Developmental speed and chronological time exert opposing effects on the spontaneous mutation rate in

Burak Bulut, Markus Pfenninger

Abstract read
In one paragraph

Article in Evolution letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Burak BulutDepartment of Molecular Ecology, Senckenberg Biodiversity and Climate Research Centre, Georg-Voigt-Str. 14-16, D-60325 Frankfurt am Main, Germany.ORCID https://orcid.org/0000-0002-5824-4708
Markus PfenningerDepartment of Molecular Ecology, Senckenberg Biodiversity and Climate Research Centre, Georg-Voigt-Str. 14-16, D-60325 Frankfurt am Main, Germany.ORCID https://orcid.org/0000-0002-1547-7245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spontaneous mutation rate (μ) is shaped by two distinct forces: the passage of chronological time, inevitably associated with mutation accumulation, and the speed of development, where rapid replication contributes to error rates. Disentangling these forces has been a major challenge, particularly in ectotherms. Testing the distinct predictions of the classic replication-dependent generation length hypothesis and the time-dependent accumulation model, we experimentally assessed individuals with naturally short (15 days) and long (38 days) generation time (GT), which is mainly determined by differences in developmental speed in the midge

Indexed as

deleterious mutationsdrift-barrier hypothesisfitness costsgermline mutation ratemolecular clock

Identifiers

PMID42244807
PMCPMC13229651

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.