Evidence map›Paper›PMID 42244766›Full record

ArticlebioRxiv : the preprint server for biology2026

Glycoconjugate diversification in

Hayley L Knox, Christine A Arbour, Chaoshuang Xia, Catherine E Costello, Barbara Imperiali, Karen N Allen

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hayley L KnoxDepartment of Chemistry, Boston University, Boston, MA 02215 USA.ORCID 0000-0003-1467-309X
Christine A ArbourDepartment of Biology , Massachusetts Institute of Technology, Cambridge, MA 02139 USA.ORCID 0000-0001-6056-296X
Chaoshuang XiaCenter for Biomedical Mass Spectrometry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118 USA.ORCID 0000-0001-7076-4813
Catherine E CostelloCenter for Biomedical Mass Spectrometry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118 USA.ORCID 0000-0003-1594-5122
Barbara ImperialiDepartment of Biology , Massachusetts Institute of Technology, Cambridge, MA 02139 USA.ORCID 0000-0002-5749-7869
Karen N AllenDepartment of Chemistry, Boston University, Boston, MA 02215 USA.ORCID 0000-0001-7296-0551

Funding

SPECIFICITY IN CO- AND POST-TRANSLATIONAL MODIFICATIONR01GM039334 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ALLEN, KAREN N., IMPERIALI, BARBARA · 1993 to 2025
$8.0M
Structure and function of the monotopic phosphoglycosyl transferase superfamily: Initiators of biosynthesis of complex bacterial glycoconjugatesR01GM131627 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ALLEN, KAREN N. · 2019 to 2025
$3.1M
Legacy Support During Closure of the Mass Spectrometry Resource for Biology and MedicineR24GM134210 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2019 to 2021
$2.1M
High-Throughput De Novo Glycan SequencingR01GM132675 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HONG, PENGYU, LIN, CHENG · 2019 to 2022
$2.0M
Methods for determination of glycoprotein glycosylation similarities among disease statesR01GM133963 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZAIA, JOSEPH · 2019 to 2021
$1.4M
A Thermo-Fisher Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer SystemS10OD021728 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2018 to 2018
$1.4M
A Thermo-Fisher Scientific Q-Exactive HF Mass Spectrometry SystemS10OD021651 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZAIA, JOSEPH · 2016 to 2016
$580k
Design and synthesis of nucleoside-based small molecules to inhibit phosphoglycosyl transferasesF32GM136023 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ARBOUR, CHRISTINE · 2020 to 2023
$234k
Defining structure and function of GT-A fold enzymes in bacterial glycan assemblyF32GM149160 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KNOX, HAYLEY · 2023 to 2024
$143k
NIGMS NIH HHS F32 GM136023NIGMS NIH HHS F32 GM149160NIGMS NIH HHS R01 GM039334NIGMS NIH HHS R01 GM131627NIGMS NIH HHS R01 GM132675NIGMS NIH HHS R01 GM133963NIGMS NIH HHS R24 GM134210NIH HHS S10 OD021651NIH HHS S10 OD021728
6 · The paper itself

Abstract

Bacterial glycoconjugates are structurally diverse, with enormous variation in sugar identity, modifications and linkages. Glycoconjugates play key roles in numerous cell functions, acting as the primary interface with the environment. Asparagine (

Identifiers

PMID42244766
PMCPMC13232197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.