Evidence map›Paper›PMID 42244758›Full record

ArticlebioRxiv : the preprint server for biology2026

Toxin resistance in the monarch butterfly expanded its milkweed host range.

Naama C Weksler, Michael Astourian, Derrick Yip, Elizabeth Ordeman, Kirsten Verster, Boris Korablev, Susan L Bernstein, Anurag A Agrawal, Noah K Whiteman, Marianthi Karageorgi

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Naama C WekslerDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-6437-3530
Michael AstourianDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.
Derrick YipDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.
Elizabeth OrdemanDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.
Kirsten VersterDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-1797-7497
Boris KorablevDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.
Susan L BernsteinDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.
Anurag A AgrawalDepartment of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY, USA.ORCID 0000-0003-0095-1220
Noah K WhitemanDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0003-1448-4678
Marianthi KarageorgiDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0003-2934-7019

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A central problem in ecology and evolution is to understand the extent to which herbivorous insect host plant specialization has been shaped by bottom-up natural selection from host-plant chemical defenses or top-down natural selection from natural enemies. Here, we show that the stepwise evolution of ATPα target-site insensitivity (TSI) in the monarch butterfly lineage consistently tracked a dietary association with cardenolide-defended

Identifiers

PMID42244758
PMCPMC13232084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.