Evidence map›Paper›PMID 42244697›Full record

ArticlebioRxiv : the preprint server for biology2026

Rapid reduction in global chromatin loop size after acute STAG2 reconstitution in human cancer cells.

Tianyi Yang, Jung-Sik Kim, Clara Mellows, Wanying Xu, Alvin Ya, Lisa Sadzewicz, Luke Tallon, Jann Sarkaria, Fulai Jin, Todd Waldman

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Tianyi YangThe Biomedical Sciences Training Program, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Jung-Sik KimDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, District of Columbia, USA.
Clara MellowsDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, District of Columbia, USA.
Wanying XuThe Biomedical Sciences Training Program, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Alvin YaDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, District of Columbia, USA.
Lisa SadzewiczInstitute for Genome Sciences, University of Maryland, Baltimore, Maryland, USA.
Luke TallonInstitute for Genome Sciences, University of Maryland, Baltimore, Maryland, USA.
Jann SarkariaDepartment of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA.
Fulai JinDepartment of Genetics and Genome Sciences, Case Comprehensive Cancer Center, Case Western Reserve School of Medicine, Cleveland, Ohio, USA.
Todd WaldmanDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, District of Columbia, USA.

Funding

STAG2 mutations and 3D genome organization in glioblastoma multiformeR01CA267872 · NCI · GEORGETOWN UNIVERSITY · PI Fulai Jin, TODD A WALDMAN · 2022 to 2026
$2.7M
NCI NIH HHS R01 CA267872
6 · The paper itself

Abstract

Truncating mutations in the tumor suppressor

Identifiers

PMID42244697
PMCPMC13232337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.