Evidence map›Paper›PMID 42244630›Full record

ArticlebioRxiv : the preprint server for biology2026

A framework for identifying transcript orthologs: the evolution of sex bias in alternative transcript structure in Drosophila.

Kinfeosioluwa S Bankole, Lauren M McIntyre, Michael Garan, Alison M Morse, Netanya Keil, Ashlee Hernandez, Olga Barmina, Mursalin Khan, Artyom Kopp, Rebekah L Rogers and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kinfeosioluwa S BankoleDepartment of Molecular Genetics and Microbiology, University of Florida.
Lauren M McIntyreDepartment of Molecular Genetics and Microbiology, University of Florida.ORCID 0000-0002-0077-3359
Michael GaranDepartment of Molecular Genetics and Microbiology, University of Florida.
Alison M MorseDepartment of Molecular Genetics and Microbiology, University of Florida.
Netanya KeilDepartment of Molecular Genetics and Microbiology, University of Florida.ORCID 0009-0006-3921-7778
Ashlee HernandezDepartment of Molecular Genetics and Microbiology, University of Florida.
Olga BarminaCollege of Biological Sciences, University of California, Davis.
Mursalin KhanThe University of Mississippi Medical Center, The University of Mississippi.
Artyom KoppCollege of Biological Sciences, University of California, Davis.
Rebekah L RogersDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte.ORCID 0000-0003-4678-4464
Rita M GrazeDepartment of Biological Sciences, Auburn University.

Funding

New Genes and AdaptionR35GM133376 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI Rebekah Lee Rogers · 2019 to 2026
$2.4M
Allele Specific Regulation of Context Specific GRNR01GM128193 · NIGMS · UNIVERSITY OF FLORIDA · PI MCINTYRE, LAUREN M. · 2018 to 2021
$1.5M
NIGMS NIH HHS R01 GM128193NIGMS NIH HHS R35 GM133376
6 · The paper itself

Abstract

Background: Recent advances in long read technologies provide an unprecedented opportunity to study transcript evolution. However, comparative evolutionary studies, even in Drosophila, are limited by inconsistent and incomplete annotation, and the lack of annotated transcript homology. Results: In this study of five species spanning 28 million years ( Conclusions: Conserved alternative transcripts suggest that transcriptional diversity is a pervasive driver of the evolution of functional diversity.

Indexed as

alternative splicingintralocus conflictsex-biased gene expressionsexual antagonismTranscript orthology

Identifiers

PMID42244630
PMCPMC13232068

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.