ArticleInternational journal of clinical and experimental pathology2026
Myolipoma of the uterus with bizarre-nucleated cells: a case report and literature review.
Article in International journal of clinical and experimental pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMyolipoma is a rare benign mesenchymal tumor composed of mature adipose tissue, smooth muscle bundles and blood vessels, which predominantly occurs in the retroperitoneum, inguinal region and abdominal wall. Primary uterine involvement is extremely uncommon, and the presence of bizarre-nucleated cells within such tumors is even rarer. The morphological features of these cells may mimic malignant neoplasms, posing great challenges for clinical and pathological diagnosis.
methodsWe report a 61-year-old female patient with imaging and ultrasonographic findings suggestive of a uterine space-occupying lesion. Histopathological examination and immunohistochemical staining were performed on the surgically resected specimen, with the detected markers including smooth muscle actin (SMA), Desmin, HMB45, Melan A, S-100 and Ki-67.
resultsPelvic magnetic resonance imaging (MRI) revealed a well-demarcated heterogeneous signal mass in the anterior wall of the uterine corpus, consistent with the manifestations of a benign tumor containing adipose components. Gross examination showed a well-circumscribed intramural mass of the uterus with a grayish-yellow and heterogeneous cut surface. Microscopically, mature adipocytes and benign smooth muscle cells were scattered with bizarre-nucleated cells characterized by markedly enlarged and irregular nuclei; no mitotic figures or necrotic foci were identified. Immunohistochemically, the smooth muscle component showed diffuse and strong positivity for SMA and Desmin, while HMB45, Melan A and S-100 were all negative. The Ki-67 proliferation index was extremely low (<1%), confirming the diagnosis of uterine myolipoma with bizarre-nucleated cells.
conclusionUterine myolipoma with bizarre-nucleated cells is an exceedingly rare benign tumor, and no recurrence or metastasis was observed during postoperative follow-up, indicating its indolent biological behavior. Accurate diagnosis requires the combination of imaging features, adequate sampling, meticulous histological evaluation and targeted immunohistochemical detection to distinguish it from leiomyosarcoma, liposarcoma and perivascular epithelioid cell tumor (PEComa).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.