ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2026
[Joint predictive effect of systolic blood pressure variability and sleep patterns on stroke].
Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesSystolic blood pressure variability (SBPV) and unhealthy sleep patterns have been identified as risk factors for stroke. However, whether the coexistence of these two factors further increases the risk of stroke remains unclear. This study aims to investigate the joint predictive effect of these two factors on stroke.
methodsA total of 219 376 participants from the UK Biobank were included in this study. SBPV was defined as the standard deviation of all systolic blood pressure measurements recorded within the previous 5 years, with at least three measurements ranging from 60 to 300 mmHg (1 mmHg=0.133 kPa). Participants were categorized into 4 quartile groups (
resultsAfter full adjustment for covariates, compared with participants with a healthy sleep pattern and SBPV in the first quartile (
conclusionsSBPV and poor sleep patterns have a multiplicative interactive predictive effect on stroke risk, highlighting the importance of simultaneously improving SBPV and sleep patterns.
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