ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2026
[Impact of urban economic level on glycemic control in patients with type 1 diabetes mellitus using do
Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesDo-it-yourself artificial pancreas systems (DIYAPS) have gradually been applied in glycemic management for patients with type 1 diabetes mellitus (T1DM). However, differences in glycemic outcomes among individuals from different socioeconomic backgrounds remain unclear. This study aimed to investigate the impact of urban economic level on glycemic control in Chinese patients with T1DM using DIYAPS.
methodsThis real-world study recruited patients with T1DM from online diabetes communities between September 2019 and February 2024. The study population covered 82 cities across 26 provinces in China, and all participants used AndroidAPS system. Demographic characteristics, physical examination data, laboratory parameters, and continuous glucose monitoring (CGM) data were collected. New first-tier and first-tier cities were classified as the developed-city group, whereas second-tier and third-tier cities were classified as the developing-city group. Glycemic metrics during different time periods were compared between the 2 groups. Univariate and multivariate Logistic regression models were used to analyze the association between the low blood glucose index (LBGI) and urban economic level in patients with T1DM.
resultsA total of 124 patients with T1DM were enrolled, including 56 patients (45.2%) from developed cities and 68 patients (54.8%) from developing cities. Among them, 52 patients (41.9%) were male and 72 patients (58.1%) were female. The median age was 22.3 (9.3, 32.5) years, and the median disease duration was 0.8 (0, 8.8) years. No statistically significant difference was observed between the two groups in all-day time in range (TIR) [percentage of time with glucose levels 3.9-7.8 mmol/L, TIR(7.8)] (
conclusionsUrban economic level has an important impact on glycemic control in patients with T1DM using DIYAPS. Higher urban economic level is associated with a lower risk of hypoglycemia in patients with T1DM.
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