Evidence map›Paper›PMID 42244278›Full record

ArticleAnnals of dermatology2026

Clinical Efficacy and Scalp Microbiome Changes Induced by AMPamide-Containing Shampoo in Patients With Seborrheic Dermatitis.

Yi Na Yoon, Sae Hee Kim, Ji Won Lim, Myeong Jae Kim, Hye-Jin Kim, Woo Jun Sul, Daehwan Kim, Wonseok Jeong, Jeonghwan Hwang, Da-Ae Yu and 2 more

Abstract read
In one paragraph

Article in Annals of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yi Na YoonDepartment of Dermatology, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8050-1750
Sae Hee KimDepartment of Dermatology, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0003-1486-626X
Ji Won LimDepartment of Dermatology, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0000-2069-8053
Myeong Jae KimDepartment of Systemic Biotechnology, Chung-Ang University, Anseong, Korea.ORCID https://orcid.org/0009-0002-2158-8483
Hye-Jin KimDepartment of Systemic Biotechnology, Chung-Ang University, Anseong, Korea.ORCID https://orcid.org/0000-0001-6008-470X
Woo Jun SulDepartment of Systemic Biotechnology, Chung-Ang University, Anseong, Korea.ORCID https://orcid.org/0000-0002-7016-1454
Daehwan KimCRID Center, Neopharm Co., Ltd., Daejeon, Korea.ORCID https://orcid.org/0009-0000-5677-0467
Wonseok JeongCRID Center, Neopharm Co., Ltd., Daejeon, Korea.ORCID https://orcid.org/0009-0008-9653-8900
Jeonghwan HwangCRID Center, Neopharm Co., Ltd., Daejeon, Korea.ORCID https://orcid.org/0009-0007-1401-8809
Da-Ae YuDepartment of Dermatology, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8158-9766
Yong Beom ChoeDepartment of Dermatology, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3074-7602
Yang Won LeeDepartment of Dermatology, Konkuk University School of Medicine, Seoul, Korea. 20050078@kuh.ac.kr.ORCID https://orcid.org/0000-0003-1268-1248

Funding

Neopharm Co., Ltd.
6 · The paper itself

Abstract

backgroundSeborrheic dermatitis (SD) is a chronic inflammatory scalp disorder associated with

objectiveTo evaluate the clinical efficacy and scalp microbiome changes following 4 weeks of use of an AMPamide-containing shampoo in patients with SD.

methodsIn this observational study, 30 patients with SD applied an AMPamide-containing shampoo for 4 consecutive weeks. Clinical outcomes, including sebum levels and overall severity scores, were assessed. Scalp bacterial and fungal communities were analyzed to evaluate α- and β-diversity and changes in

resultsTreatment resulted in significant reductions in sebum levels and clinical severity scores, particularly in erythema, dandruff, and pruritus. Bacterial community composition remained largely stable, while fungal α-diversity increased, and β-diversity analysis revealed a decrease in the ratio of

conclusionAMPamide-containing shampoo was associated with improved clinical symptoms and a shift toward a more balanced fungal community composition in patients with SD, supporting its potential as a non-steroidal therapeutic option for SD.

Indexed as

BacteriaDandruffFungiMicrobiotaSeborrheic dermatitis

Identifiers

PMID42244278
PMCPMC13243711

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.