Evidence map›Paper›PMID 42244250›Full record

ArticleInsect molecular biology2026

Transcriptional responses of Aedes aegypti chemosensory tissues in response to volatile DEET and citronella oil.

Ivan Drahun, Jessica M Sparrow, Cody W Koloski, Bryan J Cassone

Abstract read
In one paragraph

Article in Insect molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ivan DrahunDepartment of Biology, Brandon University, Brandon, Manitoba, Canada.
Jessica M SparrowDepartment of Biology, Brandon University, Brandon, Manitoba, Canada.
Cody W KoloskiDepartment of Biology, Brandon University, Brandon, Manitoba, Canada.ORCID https://orcid.org/0000-0001-5133-6135
Bryan J CassoneDepartment of Biology, Brandon University, Brandon, Manitoba, Canada.ORCID https://orcid.org/0000-0003-3479-5676

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2023-04126
6 · The paper itself

Abstract

DEET and citronella oil are two of the most widely used mosquito repellents; however, their impact on chemosensory tissues is not fully understood. In their vapour phase, the repellency effect involves the olfactory system, with mosquitoes detecting and responding to diverse odorants through their antennae and mouthparts (maxillary palps and proboscis). In this study, we first performed repellency behavioural assays that indicated both DEET and citronella effectively impaired female Aedes aegypti host-seeking capabilities (i.e. landing on a host and taking a blood meal). We next used RNA sequencing to assess global gene expression changes in Ae. aegypti antennae, mouthparts and headless bodies in response to volatile repellent exposure. The resultant transcriptional changes were considerably greater in the mosquito mouthparts than in the other tissues. The most notable responses in olfactory-related genes to both repellents were the suppressed expression of the three subunits comprising the mosquito CO

Indexed as

AedesDEETInsect RepellentsPlant OilsAnimalsArthropod AntennaeFemalecitronella oilDEETInsect RepellentsPlant Oilscarbon dioxidechemosensationgustatory receptorsolfactionphysiologyrepellents

Identifiers

PMID42244250
PMCPMC13551536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.