ArticleKnee surgery & related research2026
Increased joint line obliquity is associated with lateral cartilage degeneration after medial opening wedge high tibial osteotomy: a quantitative MRI analysis.
Article in Knee surgery & related research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Comparison of Patellofemoral Degeneration After Three Types of High Tibial Osteotomy: Retrotuberosity Biplane Open-Wedge, Supratuberosity Biplane Open-Wedge, and Closed-Wedge Techniques.Orthopaedic journal of sports medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundJoint line obliquity (JLO) often increases after medial opening wedge high tibial osteotomy (MOWHTO), and excessive JLO may adversely affect the lateral compartment. However, its effects on cartilage tissue and postoperative outcomes remain unclear. This study investigated whether increased postoperative JLO is associated with early cartilage changes on quantitative MRI T2 mapping and differences in clinical outcomes.
methodsA total of 33 knees undergoing MOWHTO were retrospectively reviewed. Radiographic parameters-hip-knee-ankle angle (HKA), medial proximal tibial angle (MPTA), and JLO-were assessed preoperatively and at 6 months. Based on postoperative radiographic measurements, patients were classified as increased JLO/MPTA (Group I: JLO > 5° and/or MPTA > 94°) or acceptable range JLO/MPTA (Group A: JLO < 5° and MPTA < 94°). Quantitative MRI T2 mapping was performed preoperatively and at 12 months to measure T2 relaxation times (T2 values) and ΔT2 values (postoperative-preoperative) in the patella, trochlea, lateral femoral condyle (LFC), and lateral tibial plateau (LTP), analyzing superficial, deep, and total cartilage layers. Knee Injury and Osteoarthritis Outcome Score (KOOS) was assessed at both time points.
resultsGroup I included 13 patients and group A included 20 patients. Postoperative HKA was similar between groups (p = 0.326). No significant intergroup differences were observed in preoperative or postoperative T2 values in the patellofemoral or lateral compartments. However, ΔT2 values in the LTP were significantly higher in group I than in group A in the superficial (3.3 ± 6.5 versus -1.7 ± 5.9 ms, p = 0.022) and total (4.5 ± 5.7 versus - 0.6 ± 5.0 ms, p = 0.012) layers. Group I also had worse KOOS-Symptoms (p = 0.016), QOL (p = 0.022), and Sport/Rec (p = 0.040).
conclusionsEven with similar postoperative limb alignment, increased JLO/MPTA was associated with early degenerative changes in lateral tibial cartilage and worse clinical outcomes. Maintaining postoperative JLO within the acceptable range during MOWHTO may help maintain lateral compartment cartilage health and optimize clinical outcomes. LEVEL OF EVIDENCE: Level IV.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.