Evidence map›Paper›PMID 42243809›Full record

Observational studyBMC health services research2026

Exploring the implementation of a long COVID rehabilitation intervention: a mixed-methods process evaluation.

Trine Brøns Nielsen, Dorthe Sørensen, Jemma Hawkins, Claus Vinther Nielsen, Steffen Leth, Berit Schiøttz-Christensen, Cecilia Hee Laursen, Lisa Gregersen Oestergaard

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06544382 (Rehabilitation and Return to Everyday Life for Patients With Long COVID), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06544382 active not recruitingnot on this map

Rehabilitation and Return to Everyday Life for Patients With Long COVID

TypeobservationalSponsorDefactum, Central Denmark RegionRan2020 to 2026Enrolled914ConditionsLong COVIDArmsThe Long COVID Rehabilitation Intervention, Usual care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Trine Brøns NielsenDEFACTUM, Central Denmark Region, Aarhus, Denmark. trbnil@rm.dk.
Dorthe SørensenResearch Centre for Care and Rehabilitation, VIA University College, Aarhus, Denmark.
Jemma HawkinsCentre for Development, Evaluation, Complexity and Implementation in Public Health Improvement (DECIPHer), School of Social Sciences, Cardiff University, Cardiff, UK.
Claus Vinther NielsenDEFACTUM, Central Denmark Region, Aarhus, Denmark.
Steffen LethDepartment of Infectious Diseases and Internal Medicine, Gødstrup Hospital, Herning, Denmark.
Berit Schiøttz-ChristensenResearch Unit of General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.
Cecilia Hee LaursenDepartment of Public Health, Faculty of Health, Aarhus University, Aarhus, Denmark.
Lisa Gregersen OestergaardDEFACTUM, Central Denmark Region, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong COVID is recognised as a global public health concern, creating demand for rehabilitation. Despite a growing evidence base on long COVID rehabilitation interventions, knowledge of the implementation of these interventions remains limited, constraining adaptation and transfer across health care settings. In a previous study, the programme theory of a Danish community-based long COVID rehabilitation intervention was refined. However, uncertainties regarding its implementation remain. This study therefore aimed to explore the delivery and implementation of The Long COVID Rehabilitation Intervention.

methodsThis convergent mixed-methods process evaluation focused on what was delivered (reach, fidelity, and dose) and how it was delivered (implementation processes and adaptations). Quantitative data comprised baseline patient questionnaires and routine rehabilitation patient records. Qualitative data comprised a focus group interview with health professionals and an individual interview with the rehabilitation centre manager. Quantitative data were analysed descriptively, and qualitative data were analysed using content analysis. Findings were integrated narratively.

resultsIn total, 336 patients were included of whom 325 patients were referred for rehabilitation and 321 initiated the programme. Most patients were female, had a long education and were employed or enrolled in education prior to their COVID-19 disease. Median rehabilitation length was 183 days (IQR 131-261), and the patients received a median of 13 sessions (IQR 8-22). Overall, key intervention activities were consistently delivered. Most rehabilitees received a combination of individual and group-based sessions, with the energy management group being the most common. Variation over time was observed in median rehabilitation length and number of sessions delivered, reflecting adaptations to the intervention over time. Adaptations and implementation were influenced by contextual conditions concerning flexible delivery within a clear structure, knowledge of long COVID, space for reflection and adaptation, and organisational recognition and legitimacy.

conclusionsThis paper reports the implementation and delivery of The Long COVID Rehabilitation Intervention and highlights key contextual conditions that shaped these processes. These findings may inform adaptation and transfer of similar rehabilitation interventions to other health care settings. Future development and adaptation of long COVID rehabilitation should explicitly consider equity in access to ensure rehabilitation services reach diverse patient groups.

trial registrationClinicalTrials.gov, NCT06544382. Registered retrospectively on 9 August 2024.

Indexed as

Post-Acute COVID-19 SyndromeAdultAgedDenmarkFemaleFocus GroupsHumansMaleMiddle AgedProgram EvaluationQualitative ResearchSurveys and QuestionnairesHealth services researchImplementationLong COVIDMixed methodsProcess evaluationRehabilitation

Identifiers

PMID42243809
PMCPMC13459222

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.