Evidence map›Paper›PMID 42243715›Full record

ArticleBMC cardiovascular disorders2026

Incidence and predictors of stroke among hypertension patients in Awi Zone public hospitals, Northwest Ethiopia: Retrospective follow-up study.

Animut Takele Telayneh, Negese Getie Eneyew, Habtamu Temesgen, Muluken Teshome

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Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Animut Takele TelaynehDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia. animuttakele@gmail.com.ORCID http://orcid.org/0000-0002-8707-4963
Negese Getie EneyewBanja Woreda Health Office, Injibara, Amhara, Ethiopia.
Habtamu TemesgenDepartment of Human Nutrition, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Muluken TeshomeDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke is a medical emergency neurologic dysfunction that occurs when blood flow to the brain is interrupted, due to a blockage or bleeding lasting ≥ 24 h, resulting in brain cell death and severe complications. It is the second most common cause of death, next to coronary heart disease. There are limited findings on the incidence of stroke among hypertension patients in Ethiopia.

objectivesTo assess the incidence and predictors of stroke among hypertensive patients at Awi Zone public hospitals, Northwest Ethiopia.

methodsA hospital-based retrospective follow-up study was conducted among adult hypertensive patients in Awi public hospitals between April 1, 2016 and March 30, 2023. A computer-generated simple random sampling method was used to select 510 study participants. Data were entered using EpiData version 4.6 and Stata version 17 for coding, cleaning, and analysis. In bi-variable analysis, variables with a p-value < 0.25 were selected for multivariable Cox proportional regression analysis. Finally, in multivariable analysis, variables with a p-value < 0.05, and 95% CI with their AHR were used to declare them as predictors.

resultsThe incidence rate of stroke was 5.53 per 100 person-years [95% CI: 4.60, 6.65]. Rural residence [AHR: 1.88 (95% CI: 1.13, 3.12)], family history of stroke [AHR: 2.52 (95% CI: 1.33, 4.77)], Atrial fibrillation [AHR: 3.10 (95% CI: 1.62, 5.90)], total cholesterol ≥ 200 mg/dl [AHR: 4.42 (95% CI: 2.71, 7.23)], overweight [AHR: 1.82 (95% CI: 1.16, 2.87)], and low-density lipoprotein-cholesterol ≥ 100 mg/dl [AHR: 1.77 (95% CI: 1.11, 2.83)] were statistically significant.

conclusionsIn this study, the incidence rate of stroke was 5.5 per 100 person-years. Rural residence, overweight, atrial fibrillation, high levels of cholesterol and low-density lipoprotein-cholesterol, and a positive family history of stroke were identified as predictors of stroke. To lower the incidence of stroke among hypertension patients, patients should adopt healthy lifestyles such as weight loss and healthy eating, and healthcare professionals should pay special attention to patients presenting with known risk factors.

Indexed as

Blood PressureHospitals, PublicHypertensionStrokeAdultAgedEthiopiaFemaleHumansIncidenceMaleMiddle AgedPrognosisRetrospective StudiesRisk AssessmentRisk FactorsEthiopiaHypertensionIncidence of strokePredictorRetrospective follow-up

Identifiers

PMID42243715
PMCPMC13459235

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