SynthesisBMC infectious diseases2026
Prevalence of Schistosoma haematobium and Schistosoma mansoni co-infection in sub-saharan Africa: a systematic review and meta-analysis.
Synthesis in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSchistosomiasis remains a significant public health challenge, especially in Sub-Saharan Africa (SSA). While individual species prevalence is well documented, the global burden of concurrent co-infection remains poorly quantified, despite its significant clinical and therapeutic implications. This study determined the prevalence of Schistosoma haemtobium (Sh) and Schistosoma mansoni (Sm) co-infection in SSA and its variation with age and geographical location.
methodsFollowing PRISMA guidelines, a systematic search of PubMed, African Journal Online, EMBASE and Google Scholar for studies published between 1980 and 2025 reporting Sh and Sm co-infection was conducted. A random-effects model was used to estimate pooled prevalence, with subgroup analyses conducted by geographical region and age. The study protocol was registered with PROSPERO (CRD420251176915).
resultsTwenty-six studies involving 33,121 participants across 11 African countries were included. The overall pooled prevalence of Schistosoma co-infection was 19.1% [95% CI; 12.3%-27.0%, I
conclusionThe prevalence of Schistosoma co-infection is substantial in SSA, particularly within the West African subregion. However, the high heterogeneity observed in this study necessitates a cautious interpretation of the data. CLINICAL TRIAL NUMBER: Not applicable.
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