Evidence map›Paper›PMID 42243694›Full record

ArticleBMC plant biology2026

ThGRF5, a 14-3-3 protein, acts as a positive regulator of salt tolerance in Tamarix hispida.

Yuanyuan Wang, Ya Nan Jing, Menghua Lv, Qianqian Chen, Youzi Tian, Caiqiu Gao, Guojun Zhang

Abstract read
In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuanyuan WangCollege of Horticulture Science and Technology (Hebei Normal University of Science and Technology), Qinhuangdao, 066004, China.
Ya Nan JingCollege of Horticulture Science and Technology (Hebei Normal University of Science and Technology), Qinhuangdao, 066004, China.
Menghua LvCollege of Horticulture Science and Technology (Hebei Normal University of Science and Technology), Qinhuangdao, 066004, China.
Qianqian ChenCollege of Horticulture Science and Technology (Hebei Normal University of Science and Technology), Qinhuangdao, 066004, China.
Youzi TianCollege of Horticulture Science and Technology (Hebei Normal University of Science and Technology), Qinhuangdao, 066004, China.
Caiqiu GaoState Key Laboratory of Tree Genetics and Breeding (Northeast Forestry University), Harbin, 150040, China. gaocaiqiu@nefu.edu.cn.
Guojun ZhangCollege of Horticulture Science and Technology (Hebei Normal University of Science and Technology), Qinhuangdao, 066004, China. zhangguojun-8@163.com.

Funding

Hebei Agriculture Research System HBCT2024200202Hebei Province Central Guiding Local Government Development Fund in Science and Technology 254Z6301GHebei Provincial Department of Science and Technology 21326301DOpen Fund of the State Key Laboratory of Tree Genetics and Breeding TGBOP2025003Scientific Research Foundation of Hebei Normal University of Science and Technology 2024YB012
6 · The paper itself

Abstract

backgroundThe 14-3-3 proteins, also known as General Regulatory Factors (GRFs), are a family of highly conserved acidic proteins that mediate cellular processes and plant stress adaptation through protein-protein interactions. In this study, 9 GRF genes (ThGRF1-ThGRF9) were isolated and characterized from the halophytic species Tamarix hispida.

resultsqRT-PCR analyses showed that all nine ThGRFs responded to multiple stress response pathways. In particular, the expression levels of ThGRF4 and ThGRF5 were significantly upregulated in T. hispida roots under salt stress, suggesting their potential involvement in salt stress responses. Furthermore, an overexpression vector of ThGRF5 was constructed and transiently transformed into T. hispida. Biochemical staining and physiological parameter analyses showed that overexpression of ThGRF5 increased antioxidant enzyme activity, decreased MDA content and electrolyte leakage by decreasing the accumulation of ROS, thereby improving tolerance to salt stress.

conclusionsThese results suggested that ThGRF5 might play an important physiological role in salt tolerance in transgenic T. hispida plants. This study provides a foundation for further elucidation of salt tolerance mechanisms involving ThGRF5 in T. hispida.

Indexed as

14-3-3 ProteinsPlant ProteinsSalt ToleranceTamaricaceaeGene Expression Regulation, PlantPlants, Genetically Modified14-3-3 ProteinsPlant Proteins14–3-3 proteinGene functionGRFsSalt stressTamarix hispida

Identifiers

PMID42243694
PMCPMC13455425

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.