Evidence map›Paper›PMID 42243687›Full record

ArticleBMC plant biology2026

The genome of Cynanchum thesioides (Freyn) K. Schum provides insights into its systematics and candidate genes potentially associated with drought tolerance as a xerophyte.

Xiaoyan Zhang, Xiaoyao Chang, Dong Zhang, Yangyang Li, Zhenfan Wang, Zhongren Yang, Fenglan Zhang

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Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Xiaoyan ZhangCollege of Horticultural and Plant Protection, Inner Mongolia Key Laboratory of Wild Peculiar Vegetable Germplasm Resource and Germplasm Enhancement, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Xiaoyao ChangCollege of Horticultural and Plant Protection, Inner Mongolia Key Laboratory of Wild Peculiar Vegetable Germplasm Resource and Germplasm Enhancement, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Dong ZhangCollege of Horticultural and Plant Protection, Inner Mongolia Key Laboratory of Wild Peculiar Vegetable Germplasm Resource and Germplasm Enhancement, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Yangyang LiCollege of Horticultural and Plant Protection, Inner Mongolia Key Laboratory of Wild Peculiar Vegetable Germplasm Resource and Germplasm Enhancement, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Zhenfan WangCollege of Horticultural and Plant Protection, Inner Mongolia Key Laboratory of Wild Peculiar Vegetable Germplasm Resource and Germplasm Enhancement, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Zhongren YangCollege of Horticultural and Plant Protection, Inner Mongolia Key Laboratory of Wild Peculiar Vegetable Germplasm Resource and Germplasm Enhancement, Inner Mongolia Agricultural University, Hohhot, 010018, China. yangzhongren_200@163.com.
Fenglan ZhangCollege of Horticultural and Plant Protection, Inner Mongolia Key Laboratory of Wild Peculiar Vegetable Germplasm Resource and Germplasm Enhancement, Inner Mongolia Agricultural University, Hohhot, 010018, China. nmndzhangfenglan@imau.edu.cn.

Funding

Double First-Class Initiative Funding - 2023 Research Start-up Grants for Introducing High-level and Outstanding Doctoral Talents NDYB2023-50Inner Mongolia Natural Science Foundation 2025QN03142
6 · The paper itself

Abstract

backgroundCynanchum thesioides (Freyn) K. Schum is an important xerophytic plant, renowned for its exceptional drought resistance. However, the genetic basis of its adaptation to extreme arid environments remains largely unknown, and the candidate genes potentially involved have yet to be identified. Additionally, as a unique resource plant, this species requires clarification of its precise phylogenetic position. Analysis of the C. thesioides genome will provide critical resources for elucidating its key drought resistance mechanisms and taxonomic status.

resultsWe generated a chromosome-level genome assembly of C. thesioides with a total size of 242 Mb. Phylogenetic analysis placed it within the Apocynaceae family, where it is closely related to A. pictum and C. roseus. Compared to other species in the order Gentianales, C. thesioides had significantly expanded gene families. These families were functionally enriched in pathways related to the biosynthesis of stilbenoids, phenylpropanoids, and flavonoids-processes that were commonly associated with drought responses. Additionally, integrative genomic and transcriptomic analyses revealed expression changes in genes involved in lignin biosynthesis. Notably, key gene families such as POD and Laccase showed marked clustering on chromosomes 3 and 9.

conclusionIn conclusion, this work provides important information on the evolutionary development of C. thesioides (Apocynaceae). It elucidates the candidate genes underlying its exceptional drought tolerance and emphasizes the importance of integrated multi-omics approaches for studying plant adaptation to environmental stress.

Indexed as

CynanchumDrought ResistanceGenes, PlantGenome, PlantDroughtsPhylogenyApocynaceaeCynanchum thesioides (Freyn) K. SchumDrought-ToleranceGenomePhenylpropanoid metabolism

Identifiers

PMID42243687
PMCPMC13455344

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