Evidence map›Paper›PMID 42243505›Full record

SynthesisInternational orthopaedics2026

Long-term glenoid loosening, radiological and clinical outcomes in cemented all-polyethylene anatomic total shoulder arthroplasty: a systematic review and meta-analysis.

Riccardo Ranieri, Matteo Illuminati, Giacomo Delle Rose, Mario Borroni, Marco Conti, Alberto Fontanarosa, Alessandro Castagna, Raffaele Garofalo

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Riccardo RanieriIRCCS Humanitas Research Hospital, Rozzano, Italy.
Matteo IlluminatiIRCCS Humanitas Research Hospital, Rozzano, Italy. matteo.illuminati@humanitas.it.
Giacomo Delle RoseIRCCS Humanitas Research Hospital, Rozzano, Italy.
Mario BorroniIRCCS Humanitas Research Hospital, Rozzano, Italy.
Marco ContiIRCCS Humanitas Research Hospital, Rozzano, Italy.
Alberto FontanarosaOspedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, Italy.
Alessandro CastagnaIRCCS Humanitas Research Hospital, Rozzano, Italy.
Raffaele GarofaloIRCCS Humanitas Research Hospital, Rozzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnatomic total shoulder arthroplasty (aTSA) is commonly recommended for osteoarthritis, but its long-term durability remains a concern, particularly in younger, active patients. This systematic review evaluates the clinical and radiological outcomes of all-polyethylene (all-PE) glenoid components at a minimum ten year follow-up.

methodsConducted according to PRISMA guidelines, 15 studies involving 1163 procedures were identified. Inclusion required a mean follow-up exceeding nine years and the availability of radiographic analysis. Outcomes included rates of glenoid loosening, rotator cuff deficiency, clinical satisfaction, and implant survival.

resultsAt a mean 11.8 year follow-up, radiographic glenoid loosening occurred in 41.0%; (95% CI: 30.0%-52.0%) of cases. Signs of cuff deficiency were observed in 210/599 cases (44.0%; 95% CI: 33.0%-55.0%). The overall revision rate was 17.0% (95%CI: 12.0%-23.0%), while the rate of objectively unsatisfactory clinical results was 31.0% (95%CI: 23.0%-40.0%). Survival rates were 93.0% (95%CI: 91.3-94.7%) at 10 years, 85.1% (95%CI: 81.5-88.7%) at 15 years and 82.5% (95%CI: 77.3-87.8%) at 20 years. Pooled proportions with 95% confidence intervals were estimated using random-effects meta-analysis.

conclusionLong-term aTSA is associated with high rates of radiographic failure and soft-tissue insufficiency. A notable discrepancy exists between radiographic failure (41.0%) and lower revision rates (17.0%), suggesting that revision rates might under estimate actual failure. Thorough counseling regarding these cumulative failure risks is recommended for younger patients.

Indexed as

Arthroplasty, Replacement, ShoulderProsthesis FailureShoulder JointShoulder ProsthesisBone CementsHumansOsteoarthritisPolyethyleneProsthesis DesignRadiographyReoperationTreatment OutcomeBone CementsPolyethyleneATSA—Shoulder surgeryGlenoid looseningLong term clinical and radiological result

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.