Evidence map›Paper›PMID 42243337›Full record

ArticleScientific reports2026

Association of the HPV vaccination intention‒behavior gap with ehealth literacy and health beliefs among chinese female college students: cross-sectional study.

Zheng-Ai Cui, Yuan Li, Yuanju Wang, Min Lu, Xinyue Shi, Ying-Ai Cui

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Zheng-Ai CuiShunde Women and Children's Hospital of Guangdong Medical University, Foshan, 528300, China.
Yuan LiFinance Department, Guangdong Medical University, Xincheng Road No. 1, Dongguan, 523808, China. hu-csu@gdmu.edu.cn.
Yuanju WangDepartment of Gynecology, Affiliated Hospital Group of Guangdong Medical University Shenzhen Baoan Central Hospital (Baoan Central Hospital of Shenzhen), Shenzhen, 518100, China.
Min LuShunde Women and Children's Hospital of Guangdong Medical University, Foshan, 528300, China.
Xinyue ShiDepartment of Management and Law, School of Humanities and Management, Guangdong Medical University, Dongguan, 523808, China.
Ying-Ai CuiSchool of Nursing, Guangdong Medical University, Xincheng Road No. 1, Dongguan, 523808, China. xiaocui@gdmu.edu.cn.

Funding

the 2026 Dongguan Philosophy and Social Sciences Planning Youth Project 2026QN12the Guangdong Medical University Undergraduate Teaching Quality and Teaching Reform Project (2025) 1JG25040the Guangdong Medical University Undergraduate Teaching Quality and Teaching Reform Project (2025) 1JG25100the Guangdong Provincial Undergraduate Teaching Quality and Teaching Reform Project 4SG25104Pthe National College Students' Innovation and Entrepreneurship Training Program 202510571007the Special Project for Clinical and Basic Sci & Tech Innovation of Guangdong Medical University GDMULCJC2025202
6 · The paper itself

Abstract

With the strengthening of public health, Chinese female college students have shown higher levels of HPV vaccination intention, but the actual vaccination rate is very low. This significant intention-behavior gap has become a major challenge for the prevention and control of HPV among colleges and universities. This study aims to explore the intention-behavior gap for HPV vaccine uptake among Chinese female college students on the basis of eHealth literacy (eHL) and the health belief model (HBM). A cross-sectional survey was conducted from June 16 to July 16, 2024, to assess socioeconomic status, eHL and HBM among female college students at Guangdong Medical University. Descriptive statistics were calculated, and binary logistic regression analysis was performed using SPSS 29.0 to identify significant independent associations between female college students' HPV vaccination intentions and behavior. Among the 2884 valid participants with an intention to receive an HPV vaccination, only 41.3% had converted from intention to uptake (≥ 1 dose).The key influencing factors included being from urban areas (adjusted OR: 1.24; 95% CI 1.04- 1.47; p = 0.018), monthly consumption (adjusted OR: 1.24; 95% CI 1.13-1.37; p < 0.001), household income (adjusted OR: 1.10; 95% CI 1.01 -1.21; p = 0.029), and parental education level (adjusted OR: 1.23; 95% CI 1.13-1.33; p < 0.001). Moreover, the participants' eHL level positively influenced their HPV vaccination conversion rate (adjusted OR: 1.02; 95% CI 1.00-1.04; p = 0.036). For HBM, trust in formal information had a significant positive influence on HPV vaccination conversion rate (adjusted OR: 1.10; 95% CI 1.04-1.16; p = 0.002), whereas perceived behavioral barriers had a significant negative influence (adjusted OR: 0.72; 95% CI 0.66 - 0.79; p < 0.001). This study confirms a substantial HPV vaccination intention‒behavior gap among Chinese female college students, influenced by socioeconomic factors, eHL, and health beliefs-specifically trust in formal information and perceived barriers. Therefore, we suggest that targeted measures should be undertaken to reduce socioeconomic gaps, improve the eHL of those with pre-existing vaccination intention, enhance institutional trust in formal medical institutions and authoritative information channels, and reduce the psychological and practical obstacles to HPV vaccination to effectively bridge the intention-behavior gap and thereby improve vaccination coverage female college students in China.

Indexed as

Health Knowledge, Attitudes, PracticeHealth LiteracyPapillomavirus InfectionsPapillomavirus VaccinesStudentsVaccinationAdolescentAdultChinaCross-Sectional StudiesEast Asian PeopleFemaleHealth Belief ModelHuman Papillomavirus VirusesHumansIntentionPapillomavirus VaccineseHealth literacyFemale college studentsHealth belief modelHPV vaccineIntention‒behavior gapTrust

Identifiers

PMID42243337
PMCPMC13478328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.