Evidence map›Paper›PMID 42243291›Full record

ArticleScientific reports2026

Synthesis, biological activities, DFT, and molecular docking of 1,3,4-thiadiazolo[2,3-c]-1,2,4-triazine-Palladium (II) complex.

Safaa S Hassan, Kamal M Dawood, Amrajaa S Abubakr, Naglaa S Mahmoud, Nabila A Kheder

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Safaa S HassanDepartment of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt. hsafaa@sci.cu.edu.eg.
Kamal M DawoodDepartment of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt. kmdawood@sci.cu.edu.eg.
Amrajaa S AbubakrDepartment of Chemistry, Faculty of Science, University of Ajdabiya, Ajdabiya, Libya.
Naglaa S MahmoudDepartment of Industrial Pharmacy, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, P.O. 12566, Giza, Egypt.
Nabila A KhederDepartment of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A developed synthesis of 4-amino-6-methyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2 H)-one (2) was presented. Its reaction with PhNCS in ethanol afforded 3-methyl-7-(phenylamino)-4 H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one (L) via an unexpected mechanism. A combination of different characterization techniques (CHN, IR, NMR, UV-Vis TGA, XRD and MS) was utilized for comprehensive structure elucidation. [Pd(L)Cl

Indexed as

Coordination ComplexesMolecular Docking SimulationPalladiumTriazinesAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsDensity Functional TheoryHumansMicrobial Sensitivity TestsThiadiazolesAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsCoordination ComplexesPalladiumThiadiazolesTriazines[1,3,4]thiadiazole-[1,2,4]triazineAnticancer activityAntimicrobial activityComputational studiesPd(II) complexRegioselective synthesis

Identifiers

PMID42243291
PMCPMC13237342

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.