Evidence map›Paper›PMID 42242925›Full record

ArticleVox sanguinis2026

Impact of a national donor vigilance system: An example of improved donor health by reduction of delayed bleedings after donor plasmapheresis.

Pia Braagaard Hartfelt, Christina Mikkelsen, Bitten Aagaard, Rune Larsen, Sys Hasslund, Louise Ørnskov Drechsler, Mark H Yazer, Mie Topholm Bruun

Abstract read
In one paragraph

Article in Vox sanguinis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pia Braagaard HartfeltClinical Immunology Research Unit, Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0009-0005-7153-7707
Christina MikkelsenDepartment of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-2945-6197
Bitten AagaardDepartment of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark.
Rune LarsenDepartment of Clinical Immunology, Naestved University Hospital, Naestved, Denmark.ORCID https://orcid.org/0000-0002-7635-8012
Sys HasslundDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
Louise Ørnskov DrechslerDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
Mark H YazerClinical Immunology Research Unit, Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0000-0001-6740-2758
Mie Topholm BruunClinical Immunology Research Unit, Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesIn Denmark, all blood banks use the same standardized donor vigilance system, enabling comparisons of adverse reactions across the country's five regions. At several collection sites, a compression bandage is applied over the venipuncture site after donation. In this study, we investigate whether using a compression bandage is more effective than using a non-compression bandage in preventing delayed bleeding. MATERIALS AND

methodsData were collected from four of the Danish regions (data from the fifth region were incomplete) between 2021 and 2024 using the Danish donor vigilance system. In one region, compression bandage has been used consistently since 2021, whereas three other regions transitioned from non-compression bandages to compression bandages at different times during the study period.

resultsData from 426,250 donor plasmaphereses were analysed; 160,547 (37.7%) were collected without the compression bandage and 265,703 (62.3%) were collected with the bandage. A significantly lower number of delayed bleeding events occurred when the bandage was applied post-donation (0.3% vs. 0.04%, respectively, p < 0.001).

conclusionThe implementation of the compression bandage resulted in a significant decrease in delayed bleeding in Danish plasma donors. Using a compression bandage may be an easy and cost-efficient way to improve donation safety.

Indexed as

Blood DonorsHemorrhagePlasmapheresisBandagesBlood DonationDenmarkFemaleHumansMaleadverse donor reactionsdelayed bleedingdonor plasmapheresisdonor safetydonor vigilance

Identifiers

PMID42242925
PMCPMC13563485

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.