ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2026
Management and long-term serum urate control in gout: a population-based primary care cohort study.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundGout is a prevalent chronic inflammatory disease associated with a substantial clinical and cardiovascular burden. Despite the availability of effective urate-lowering therapies (ULTs), gout management remains suboptimal.
aimTo describe clinical characteristics and treatment patterns, and to identify factors associated with long-term serum urate (SU) control in gout. DESIGN AND
settingRetrospective population-based cohort study using the primary care research database 'Sistema d'Informació per al Desenvolupament de la Investigació en Atenció Primària' (SIDIAP), covering >75% of the Catalan population within a universal healthcare system.
methodIndividuals with incident gout diagnosed between 2012 and 2023 were included. Demographic, clinical, and ULT data were collected. Good SU control was defined as SU levels <6 mg/dL for ≥80% of follow-up time. Factors associated with SU control were analysed.
resultsA total of 94 759 patients were included (mean age 66.25 [standard deviation 14.64] years; 79.58% male [75 412/94 759]; median follow-up 5.44 [interquartile range 2.54-8.24] years). In the 94 759 patients, hypertension (65.15%,
conclusionLong-term SU control in gout remains poor in primary care. Early initiation of ULT, appropriate dose optimisation, and improved adherence represent key modifiable targets to improve gout management.
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