ArticleOrthopaedic surgery2026
Generalized Joint Hypermobility in Adolescent Idiopathic Scoliosis: Greater Curve Flexibility, Larger Thoracic Kyphosis, but Higher Complication Risk.
Article in Orthopaedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectivesGeneralized joint hypermobility (GJH) is prototypical clinical feature of hypermobility spectrum disorders, and emerging studies have found a correlation between GJH and structural spinal changes. This study aims to investigate the preoperative radiographic characteristics and clinical outcomes of patients with GJH and adolescent idiopathic scoliosis (AIS).
methodsPatients with AIS were prospectively recruited between July 2023 and August 2024 and divided into GJH (Beighton score ≥ 6) and non-GJH (Beighton score < 6) groups. The GJH group was matched 1:1 with controls based on age (±1 year), sex, main curve magnitude (±5°), curve type of the Lenke classification, triradiate cartilage status, and Risser stage (±1 grade). Baseline characteristics and surgical data were recorded. Preoperative and immediately postoperative radiographic parameters were measured. The Scoliosis Research Society-22 revised (SRS-22r) questionnaire was collected preoperatively and at least 1 year postoperatively. Univariate analysis and multivariable linear regression analysis were used to identify factors associated with main curve flexibility, TK, and T1 tilt angle.
resultsA total of 136 consecutive patients were included, with 29 patients (21.3%) classified into the GJH group. After mating, the GJH showed greater flexibility of the main curve (60.0% ± 27.7% vs. 45.8% ± 22.1%, p = 0.020) and increased thoracic kyphosis (22.9° ± 11.5° vs. 16.7° ± 11.7°, p = 0.031) compared to the control group. Multivariable linear regression analyses revealed that the GJH was correlated with increased spinal flexibility (β = 14.09, p = 0.015) and larger thoracic kyphosis (β = 6.11, p = 0.043). The GJH group demonstrated a relatively higher risk of surgical complications compared to the non-GJH group (17.2% [5/29] vs. 4.7% [5/107], p = 0.036). However, no significant differences were observed in patient-reported outcome measures (PROMs) between the two groups.
conclusionsIn patients with AIS, GJH is associated with increased spinal flexibility and greater thoracic kyphosis and, importantly, a higher risk of surgical complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.