Trial reportThe European respiratory journal2026
Home-based, remotely supervised, high-intensity interval training and cardiorespiratory fitness in children and adolescents with post-infectious bronchiolitis obliterans: a randomised controlled trial.
Trial report in The European respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile high-intensity interval training (HIIT) has shown effectiveness in improving cardiorespiratory fitness (CRF) across various chronic respiratory diseases, its impacts on individuals with post-infectious bronchiolitis obliterans (PIBO) remain unexplored. Our aim was to assess the effects of a home-based, remotely supervised, HIIT programme on CRF, clinical and functional variables in patients with PIBO.
methodsParticipants of this assessor-blinded, multicentre, randomised controlled trial were individuals with PIBO aged 6-20 years. An exercise (EXE) group underwent two 40-min sessions of HIIT remotely supervised in real time per week. Sessions were continued for 16 weeks. The control (CON) group adhered to general physical activity recommendations. The primary outcome was peak oxygen uptake (
results51 PIBO patients were enrolled (EXE group n=25; CON group n=26) (49% females; mean±sd age 13.3±4.2 years; forced expiratory volume in 1 s -3.56±1.28 (z-score);
conclusionsOur real-time, remotely supervised HIIT intervention was effective at significantly increasing CRF and functional capacity in children and adolescents with PIBO.
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