Evidence map›Paper›PMID 42242669›Full record

ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2026

Clinician and family perspectives on the use of single maintenance and reliever therapy for children.

Elika Eshghi, Grace Ryan, Melissa Goulding, Michelle Spano, Stephanie Simms, Deicy Mejia, Hannah Seay, Anna Bryce, Lynn B Gerald, Anna Bottar and 8 more

Abstract read
In one paragraph

Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Elika EshghiDivision of Pulmonary Medicine, Department of Pediatrics, University of Massachusetts (UMass) Chan Medical School, UMass Memorial Children's Medical Center, Worcester, Massachusetts.
Grace RyanDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, Massachusetts.
Melissa GouldingDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, Massachusetts.
Michelle SpanoDivision of Pulmonary Medicine, Department of Pediatrics, University of Massachusetts (UMass) Chan Medical School, UMass Memorial Children's Medical Center, Worcester, Massachusetts.
Stephanie SimmsDivision of Pulmonary Medicine, Department of Pediatrics, University of Massachusetts (UMass) Chan Medical School, UMass Memorial Children's Medical Center, Worcester, Massachusetts.
Deicy MejiaDivision of Pulmonary Medicine, Department of Pediatrics, University of Massachusetts (UMass) Chan Medical School, UMass Memorial Children's Medical Center, Worcester, Massachusetts.
Hannah SeayDepartment of Pediatric Pulmonology, Mass General Brigham for Children, Boston, Massachusetts.
Anna BryceDivision of Pulmonary Medicine, Department of Pediatrics, University of Massachusetts (UMass) Chan Medical School, UMass Memorial Children's Medical Center, Worcester, Massachusetts.
Lynn B GeraldOffice of Population Health Sciences, University of Illinois Chicago, Chicago, Illinois.
Anna BottarDepartment of Pediatrics, UMass Memorial Children's Medical Center, Worcester, Massachusetts.
Nancy ByattDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, Massachusetts; Lifeline for Families, Department of Psychiatry, UMass Chan Medical School, Worcester, Massachusetts; Department of Obstetrics and Gynecology, UMass Chan Medical School, Worcester, Massachusetts.
Jerry A KrishnanBreathe Chicago Center, University of Illinois Chicago, Chicago, Illinois.
Christine FrisardDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, Massachusetts.
Stephenie C LemonDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, Massachusetts.
Sybil CrawfordTan Chingfen Graduate School of Nursing, UMass Chan Medical School, Worcester, Massachusetts.
Radley SheldrickDepartment of Psychiatry and Behavioral Sciences, UMass Chan Medical School, Worcester, Massachusetts.
Lori PbertDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, Massachusetts.
Michelle TrivediDivision of Pulmonary Medicine, Department of Pediatrics, University of Massachusetts (UMass) Chan Medical School, UMass Memorial Children's Medical Center, Worcester, Massachusetts; Department of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, Massachusetts; Child Health Equity Center, Department of Pediatrics, UMass Chan Medical School, UMass Memorial Children's Medical Center, Worcester, Massachusetts. Electronic address: michelle.trivedi3@umassmed.edu.

Funding

Asthma Link: A Partnership between Pediatric Practices, Schools, and Families to Improve Medication Adherence and Health Outcomes in Children with Poorly Controlled AsthmaR01HL169229 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Michelle Trivedi · 2023 to 2026
$3.0M
Asthma Link: School Supervised Therapy to Improve Medication Adherence in Children with Poorly Controlled AsthmaK23HL150341 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI TRIVEDI, MICHELLE · 2020 to 2024
$881k
NHLBI NIH HHS K23 HL150341NHLBI NIH HHS R01 HL169229
6 · The paper itself

Abstract

backgroundSingle maintenance and reliever therapy (SMART) is the guideline-recommended treatment for children with moderate to severe asthma, yet it is underutilized in pediatric practice.

objectiveTo understand barriers and facilitators to SMART adoption within pediatric practice.

methodsWe interviewed 52 participants (16 pediatricians, 22 parents, and 16 children). Interviews were conducted until theme saturation, recorded, transcribed, coded, and qualitatively analyzed using the Consolidated Framework for Implementation Research.

resultsWe identified barriers, facilitators, and potential solutions to SMART implementation. Participants described barriers at the following levels: (1) the clinic level, which included a lack of clinician training and clinical decision support for SMART; (2) the family level, which included discomfort transitioning away from traditional albuterol and concern about SMART's effectiveness as a rescue medication; and (3) the school and systems levels, which included poor communication and a lack of aligned care plans across community settings like schools, and challenges navigating insurance coverage. Facilitators to SMART implementation included acceptance of SMART as a simpler treatment that could improve asthma symptoms. Proposed solutions to barriers included the following: (1) clinic-level trainings and integrated clinical decision support; (2) family-level support for reluctant families; and (3) clear communication between clinics and schools, access to SMART-specific medication orders and action plans, and insurance support.

conclusionMost pediatricians and families reported that SMART is a favorable, simple, and acceptable treatment approach for children with asthma. However, pediatricians and families described significant barriers to using guideline-concordant SMART in routine practice. These results could inform targeted efforts to improve the adoption of SMART within pediatric asthma care.

Indexed as

Anti-Asthmatic AgentsAsthmaChildFemaleHumansMaleParentsPediatriciansPractice Guidelines as TopicAnti-Asthmatic Agents

Identifiers

PMID42242669
PMCPMC13397430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.