Evidence map›Paper›PMID 42242582›Full record

Trial reportBrazilian journal of anesthesiology (Elsevier)

Effects of propofol versus sevoflurane induction on echocardiographic parameters in patients with mitral stenosis: a randomized clinical trial.

Mohammed Jaffer Sherif, Saravana Babu Ms, Prasanta Kumar Dash, Nagarjuna Panidappu, Subin Sukesan, Thomas Koshy

Abstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammed Jaffer SherifSree Chitra Tirunal Institute for Medical Sciences and Technology, Division of Cardiothoracic and Vascular Anesthesia, Trivandrum, India.
Saravana Babu MsAll India Institute of Medical Sciences, Department of Anesthesiology, Madurai, India. Electronic address: saravanababu4u@gmail.com.
Prasanta Kumar DashSree Chitra Tirunal Institute for Medical Sciences and Technology, Division of Cardiothoracic and Vascular Anesthesia, Trivandrum, India.
Nagarjuna PanidappuAmrita Institute of Medical Sciences, Department of Cardiothoracic and Vascular Anesthesia, Kochi, India.
Subin SukesanSree Chitra Tirunal Institute for Medical Sciences and Technology, Division of Cardiothoracic and Vascular Anesthesia, Trivandrum, India.
Thomas KoshySree Chitra Tirunal Institute for Medical Sciences and Technology, Division of Cardiothoracic and Vascular Anesthesia, Trivandrum, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe main aim of this study was to compare the effects of propofol and sevoflurane induction on the echocardiographic parameters of Mitral Stenosis (MS) patients.

methodsProspective, randomized, outcome-assessor-blinded clinical trial in 80 adults with MS undergoing mitral valve replacement. Patients were randomized to receive General Anesthesia (GA) induction with either propofol (Group P) or sevoflurane (Group S). The primary objective was to assess the changes in mean gradient after 3 minutes of GA induction. Secondary objectives were to assess the changes in echocardiographic Doppler parameters and hemodynamic variables.

resultsCompared to pre-induction values, there was significant reduction in the peak and mean gradients as well as peak velocity, in both the groups after GA induction. The Mitral Valve Area calculated by continuity equation (MVA-c) and by pressure half time (MVA-p) were increased in Group S after GA induction. On comparison between the two groups, Group S showed lower pressure half time and greater MVA-p (p = 0.0099) and MVA-c (p = 0.0316) than Group P after GA induction. Mean arterial pressure decreased at the 1

conclusionEven though both anesthetic agents reduced transvalvular gradients in MS patients, sevoflurane was associated with a greater increase in estimated valve area and a reduction in heart rate compared with propofol. These findings suggest more favorable short-term hemodynamic and echocardiographic changes with sevoflurane at the studied time points.

Indexed as

Anesthetics, InhalationAnesthetics, IntravenousMethyl EthersMitral Valve StenosisPropofolSevofluraneAdultAnesthesia, GeneralEchocardiography, DopplerFemaleHemodynamicsHumansMaleMiddle AgedProspective StudiesAnesthetics, InhalationAnesthetics, IntravenousMethyl EthersPropofolSevofluraneAnesthetics, InhalationAnesthetics, IntravenousEchocardiographyMitral valve stenosisPropofolSevoflurane

Identifiers

PMID42242582
PMCPMC13320465

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.