Evidence map›Paper›PMID 42242449›Full record

ArticleVirologica Sinica2026

A comprehensive RNA virome from molluscan transcriptomes reveals extensive diversity and modular genome evolution.

Jiaxiang Li, Kewei Chen, Xin Chen, Kaiyang Zheng, Shujuan Sun, Hao Yu, Yue Dong, Ziyue Wang, Yixuan Xu, Andrew McMinn and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virologica Sinica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jiaxiang LiMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China.
Kewei ChenMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China.
Xin ChenMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China.
Kaiyang ZhengMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China.
Shujuan SunMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China.
Hao YuMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China.
Yue DongMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China.
Ziyue WangMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China.
Yixuan XuHaide College, Ocean University of China, Qingdao, 266100, China.
Andrew McMinnMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China; UMT-OUC Joint Centre for Marine Studies, Qingdao, 266003, China; Institute for Marine and Antarctic Studies, University of Tasmania, Hobart, TAS, 7001, Australia.
Yeong Yik SungUMT-OUC Joint Centre for Marine Studies, Qingdao, 266003, China; Institute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Terengganu, 21030, Malaysia.
Wen Jye MokUMT-OUC Joint Centre for Marine Studies, Qingdao, 266003, China; Institute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Terengganu, 21030, Malaysia.
Li Lian WongUMT-OUC Joint Centre for Marine Studies, Qingdao, 266003, China; Institute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Terengganu, 21030, Malaysia.
Yantao LiangMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China; UMT-OUC Joint Centre for Marine Studies, Qingdao, 266003, China. Electronic address: liangyantao@ouc.edu.cn.
Min WangMoE Key Laboratory of Evolution and Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, 266003, China; Haide College, Ocean University of China, Qingdao, 266100, China; UMT-OUC Joint Centre for Marine Studies, Qingdao, 266003, China. Electronic address: mingwang@ouc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mollusca, the second-largest animal phylum, includes many aquaculture species used as important food resources for humans. While DNA viruses that threaten molluscan aquaculture have received much attention, molluscan RNA viromes are still understudied. Here, using a multi-stage RdRP discovery pipeline combining six-frame translation, profile-based homology search, and phylogenetic validation, 203 RNA viruses spanning five viral phyla and fifteen viral orders were identified, based on 223 molluscan metatranscriptomes covering eight classes. Phylogenetic analysis, combined with structural modeling, revealed a significant increase in the number of Pisuviricota-related lineages. Extensive modular evolution in viral genomes was observed, including gene rearrangements and co-evolution of capsid and RdRP genes. Host prediction linked 76% of the RNA viruses to a range of eukaryotes. These findings expand the diversity of RNA viruses associated with molluscs and shed light on their phylogenetic relationships, highlighting that molluscs might serve as an important reservoir of diverse RNA viruses infecting a range of eukaryotic hosts.

Indexed as

Evolution, MolecularGenome, ViralMolluscaRNA VirusesTranscriptomeViromeAnimalsGenetic VariationPhylogenyRNA, ViralRNA, ViralHost associationMetatranscriptomicsMolluscaRNA virusesVirus diversity

Identifiers

PMID42242449
PMCPMC13469297

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.