ReviewCurrent problems in cardiology2026
Determinants of cardiorespiratory fitness after successfully reperfused ST-elevation myocardial infarction.
Review in Current problems in cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundModern treatment of ST-elevation myocardial infarction (STEMI), emphasizing prompt reperfusion, has improved clinical outcomes by preserving cardiac function. Despite this, cardiorespiratory fitness remains impaired. The purpose of this study was to assess determinants of cardiorespiratory fitness in patients with reperfused STEMI and preserved cardiac function.
methodsWe prospectively collected data from two patient cohorts with reperfused STEMI who underwent cardiopulmonary exercise testing on either a semi-supine cycle ergometer (Cohort 1) or treadmill (Cohort 2). Peak oxygen consumption (VO
resultsWe included ninety-five patients (58 [51-65] years, 34% female) tested 41 [37-45] days after STEMI (Cohort 1: n = 39; Cohort 2: n = 56). Resting LVEF was 55 [50-59] %, with 2 (2%) having <40%. E' velocity was 8.8 [7.3-10.5] and E/e' was 7.6 [6.5-9.2]. Peak VO
conclusionCardiorespiratory fitness remains impaired after successfully reperfused recent STEMI, despite rather preserved resting cardiac function. Cardiac and peripheral reserve partially explain the impairments, and preserving these may improve fitness after STEMI.
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