Evidence map›Paper›PMID 42241937›Full record

Trial reportEnvironment international2026

Effects of a liquefied petroleum gas stove and fuel intervention and air pollution exposure on early childhood development: Findings from the household air pollution intervention network trial.

Lisa M Thompson, Oscar de León, Sheela Sinharoy, Viviane Valdes, Seema Das, Vigneswari Aravindalochanan, Ajay Pillarisetti, Shirin Jabbarzadeh, Kalpana Balakrishnan, Anaite Diaz-Artiga and 16 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Environment international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Lisa M ThompsonFamily Health Care Nursing, School of Nursing, University of California, San Francisco, 490 Illinois St, San Francisco, CA 94143, USA; Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. Electronic address: lisa.thompson@ucsf.edu.
Oscar de LeónGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA; Center for Health Studies, Universidad del Valle de Guatemala, 18 Avenida 11-95 Guatemala City 01015, Guatemala. Electronic address: ofdeleon@uvg.edu.gt.
Sheela SinharoyHubert Department of Global Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. Electronic address: sheela.sinharoy@emory.edu.
Viviane ValdesDivision of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, 2 Brookline Place, Brookline, MA 02445, USA. Electronic address: viviane.valdes@childrens.harvard.edu.
Seema DasNell Hodgson Woodruff School of Nursing, Emory University, 1520 Clifton Road NE, Atlanta, GA 30322, USA. Electronic address: seema.das@emory.edu.
Vigneswari AravindalochananDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Porur, Chennai 600 116, Tamil Nadu, India. Electronic address: vigneswari@ehe.org.in.
Ajay PillarisettiEnvironmental Health Sciences, School of Public Health, University of California at Berkeley, Berkeley Way West, 2121 Berkeley Way, Room 5302, Berkeley, CA 94720-7360, USA. Electronic address: ajaypillarisetti@berkeley.edu.
Shirin JabbarzadehDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. Electronic address: shirin.jabbar@emory.edu.
Kalpana BalakrishnanDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Porur, Chennai 600 116, Tamil Nadu, India. Electronic address: kalpanasrmc@ehe.org.in.
Anaite Diaz-ArtigaCenter for Health Studies, Universidad del Valle de Guatemala, 18 Avenida 11-95 Guatemala City 01015, Guatemala. Electronic address: Diaz-Artigaadiaz@uvg.edu.gt.
John P McCrackenCenter for Health Studies, Universidad del Valle de Guatemala, 18 Avenida 11-95 Guatemala City 01015, Guatemala; Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, 100 Foster Rd, Athens, GA 30606, USA. Electronic address: john.mccracken@uga.edu.
Ghislaine RosaPublic Health, Policy and Systems, University of Liverpool, Waterhouse Building, Block B, Brownlow Street, Liverpool L69 3GF, UK. Electronic address: g.abadie-rosa@liverpool.ac.uk.
Gurusamy ThangavelDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Porur, Chennai 600 116, Tamil Nadu, India.
Sankar SambandamDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Porur, Chennai 600 116, Tamil Nadu, India.
Krishnendu MukhopadhyayDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Porur, Chennai 600 116, Tamil Nadu, India.
Naveen PuttaswamyDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Porur, Chennai 600 116, Tamil Nadu, India.
Marilu ChiangBiomedical Research Unit, Asociación Benéfica PRISMA, v. Guardia Civil 1321, Oficina 1501, Surquillo, Lima, Peru. Electronic address: mchiang@prisma.org.pe.
Florien NdagijimanaEagle Research Center, # KG 176 Street, P.O Box 982, Kigali, Rwanda. Electronic address: florien.n.hapin@gmail.com.
Amy E LovvornGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. Electronic address: alovvor@emory.edu.
Kyle SteenlandGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. Electronic address: nsteenl@emory.edu.
Dana Boyd BarrGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. Electronic address: dbbarr@emory.edu.
Usha RamakrishnanHubert Department of Global Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA.
William CheckleyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E Monument Street. Suite 555, Baltimore, MD 21287, USA; Center for Global Non-Communicable Disease Research and Training, School of Medicine, Johns Hopkins University, 1830 E Monument Street. Suite 555, Baltimore, MD 21287, USA. Electronic address: wcheckl1@jhmi.edu.
Jennifer PeelDepartment of Epidemiology, Colorado School of Public Health, 700 South Mason St., Fort Collins, CO 80523, USA. Electronic address: jennifer.peel@colostate.edu.
Thomas ClasenGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. Electronic address: thomas.f.clasen@emory.edu.
Household Air Pollution Intervention Network investigators

Funding

Household Air Pollution and Health: A Multi-Country LPG Intervention TrialUM1HL134590 · NHLBI · EMORY UNIVERSITY · PI CHECKLEY, WILLIAM, CLASEN, THOMAS F · 2016 to 2021
$31.1M
NHLBI NIH HHS UM1 HL134590
6 · The paper itself

Abstract

backgroundEarly Child Development (ECD) encompasses physical, cognitive, social, and emotional changes during childhood. Air pollution exposure has been associated with ECD delays. The Household Air Pollution Intervention Network (HAPIN) randomized controlled trial evaluated the health effects of a liquefied petroleum gas cookstove and fuel intervention during pregnancy and infancy. Here we present the intervention effect and exposure-response relationship between fine particulate matter (PM

methodsThe HAPIN trial enrolled 3195 pregnant women in rural Guatemala, Peru, India, and Rwanda. ECD was assessed at 12 months of infant age using the Caregiver Reported Early Development Instruments (CREDI). Personal 24-hr PM

resultsOf 3061 live births, 2446 (79.9%) had valid CREDI assessments at 12 months. Despite substantial reductions in personal PM DISCUSSION: While the LPG stove intervention did not affect ECD outcomes, variations in timing and sex-specific differences may play a role in shaping intervention effectiveness, similar to findings we previously reported for birth outcomes.

Indexed as

Air Pollution, IndoorChild DevelopmentCookingEnvironmental ExposurePetroleumAdultAir PollutantsFemaleGuatemalaHumansIndiaInfantMaleMaternal ExposureParticulate MatterPeruAir PollutantsParticulate MatterPetroleumCaregiver Reported Early Development Instruments (CREDI)Early childhood developmentExposure–responseHousehold air pollutionIntention-to-treatParticulate matter

Identifiers

PMID42241937
PMCPMC13679734

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.