Evidence map›Paper›PMID 42241480›Full record

ArticleSchizophrenia bulletin2026

Prognostic Factors for Adulthood Psychosis in Adolescent Psychiatry Services: A Longitudinal Total Birth Cohort Study.

Ulla Lång, Kirstie O'Hare, Fiona Boland, Johanna Metsälä, Anna Pulakka, Juha Veijola, Eero Kajantie, Colm Healy, Ian Kelleher

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ulla LångInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH16 4SB, United Kingdom.ORCID 0000-0002-1399-0635
Kirstie O'HareInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH16 4SB, United Kingdom.
Fiona BolandData Science Centre, School of Population Health, RCSI University of Medicine and Health Sciences, D02 Dublin, Ireland.
Johanna MetsäläInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH16 4SB, United Kingdom.
Anna PulakkaResearch Unit of Population Health, University of Oulu, 90014 Oulu, Finland.
Juha VeijolaResearch Unit of Clinical Medicine, University of Oulu, 90014 Oulu, Finland.
Eero KajantieDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, 00271 Helsinki, Finland.
Colm HealyInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH16 4SB, United Kingdom.
Ian KelleherInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH16 4SB, United Kingdom.

Funding

Academy of Medical Sciences APR8\1005European Union Horizon 2020 Research and Innovation Programme 733280Finska LäkaresällskapetHealth Research Board ECSA-2020-005Päivikki and Sakari Sohlberg FoundationPediatric Research FoundationSigne and Ane Gyllenberg FoundationSigrid Jusélius FoundationUK Department for Business, Energy and Industrial Strategy
6 · The paper itself

Abstract

background and hypothesisAs many as half of all psychotic disorders diagnosed by age 28 in the population emerge in individuals who attended child and adolescent psychiatry services, highlighting important opportunities for psychosis prediction and prevention. An important next step is to identify prognostic factors for later psychotic disorders within this clinical population. We assessed a large number of potential prognostic factors for adult-onset psychosis within adolescent psychiatry services. STUDY

designLinked population-wide register data for all individuals born in Finland 1987-1992. Using survival analyses, we assessed a range of clinical, service use, and sociodemographic characteristics in adolescent psychiatry patients (ie, individuals who were diagnosed with a mental disorder in specialist-level services in adolescence [ages 13-17 years]) as prognostic factors for adult-onset psychotic disorders (ages 18-30 years; individuals diagnosed with psychosis before age 18 [n = 2276] were excluded). STUDY

resultsAmong adolescent psychiatry patients (n = 27 626), cumulative risk of psychosis between ages 18 and 30 was 8.5%. Within-service significant prognostic factors for psychosis included: total number of mental disorder diagnoses received in adolescence, young maternal age, premature birth, older age at first adolescent psychiatry contact, history of child psychiatry contact, psychiatric inpatient admission in adolescence, parental history of psychosis, and parental history of inpatient psychiatric admission.

conclusionsOur findings demonstrate that a number of clinical, service use, and sociodemographic factors have prognostic significance for the development of adulthood psychosis among adolescent psychiatry patients.

Indexed as

Adolescent PsychiatryMental Health ServicesPsychotic DisordersRegistriesAdolescentAdultBirth CohortFemaleFinlandHumansLongitudinal StudiesMalePrognosisYoung Adultpsychosis riskregister based studyyoung people

Identifiers

PMID42241480
PMCPMC13235725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.