Evidence map›Paper›PMID 42241474›Full record

ArticlePLoS medicine2026

Beyond associations: Navigating the safety of non-steroidal anti-inflammatory drugs (NSAIDs) in early pregnancy.

Andrew S C Yuen, Kenneth K C Man

Abstract read
In one paragraph

Article in PLoS medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew S C YuenResearch Department of Practice and Policy, School of Pharmacy, University College London, London, United Kingdom.ORCID https://orcid.org/0009-0005-4850-566X
Kenneth K C ManResearch Department of Practice and Policy, School of Pharmacy, University College London, London, United Kingdom.ORCID https://orcid.org/0000-0001-8645-1942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain and fever in pregnancy require treatment, but fetal safety concerns complicate analgesic choice. A recent PLOS Medicine study presents new evidence on the safety of first-trimester NSAID use and congenital malformation risk, but interpreting findings across studies is challenging.

Indexed as

Abnormalities, Drug-InducedAnti-Inflammatory Agents, Non-SteroidalPregnancy ComplicationsFemaleHumansPainPregnancyPregnancy Trimester, FirstAnti-Inflammatory Agents, Non-Steroidal

Identifiers

PMID42241474
PMCPMC13235903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.