ArticleIndian journal of ophthalmology2026
Safety and efficacy of modified suture techniques in Ologen augmented trabeculectomy for eyes with advanced primary open angle and angle closure glaucoma.
Article in Indian journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate the early postoperative safety and long-term efficacy of Ologen augmented trabeculectomy (Olo-trab) with releasable scleral flap suture in eyes with advanced primary open/closed angle glaucoma.
methodsThis was a single-center, prospective, interventional, and noncomparative study of patients who underwent Olo-trab for advanced glaucoma (cup disc ratio > 0.8), in whom target pressure could not be met despite maximum permissible medical therapy. Postoperatively, patients were followed up for 12 months and evaluated for early postoperative complications within 1 month. The primary surgery success rate was assessed at 6 months and 1 year.
resultsThe study cohort comprised 31 eyes of 27 patients. The mean age of the population was 59.48 ± 10.41 years. Eight cases were on two-drug antiglaucoma medications (AGMs), 13 on three drugs, and 10 were using four AGMs. The mean preoperative intraoperative pressure (IOP) of the cohort was 30.5 ± 9.1 mmHg. A total of 15 cases underwent combined phacoemulsification and trabeculectomy. Early postoperative hypotony was the only complication observed in 2/31 eyes (6%). Twelve months post surgery, 27 out of 31 eyes (87.10%) had a complete success, and the remaining 4 (12.9%) achieved a qualified/partial success. Mean postoperative IOP readings at all follow-up visits were significantly lower than those at preoperative levels ( P < 0.001).
conclusionsOlo-Trab with a releasable scleral flap suture has shown encouraging results for IOP control with a marginalized risk of postoperative hypotony in advanced cases of primary glaucoma.
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