Evidence map›Paper›PMID 42241114›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

In vivo binding by

Yamila Carla Agrofoglio, María José Iglesias, María José de Leone, Carlos Esteban Hernando, Martin Lewinski, Sol Belén Torres, Giuliana Contino, Kim Joelle Köhnke, Marcelo Javier Yanovsky, Dorothee Staiger and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Update of
    2025
5 · Who and what money

Authors and funding

11 authors.

Yamila Carla Agrofoglio *Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and Instituto de Fisiología, Biología Molecular y Neurociencias-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina.ORCID 0000-0002-0934-8754
María José Iglesias *Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and Instituto de Fisiología, Biología Molecular y Neurociencias-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina.ORCID 0000-0002-6007-5069
María José de Leone *Fundación Instituto Leloir, Instituto de Investigaciones Bioquímicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires C1405BWE, Argentina.ORCID 0000-0001-5915-0351
Carlos Esteban HernandoFundación Instituto Leloir, Instituto de Investigaciones Bioquímicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires C1405BWE, Argentina.
Martin LewinskiRNA Biology and Molecular Physiology, Faculty of Biology, Bielefeld University, Bielefeld 33615, Germany.ORCID 0000-0002-2692-3319
Sol Belén TorresUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and Instituto de Fisiología, Biología Molecular y Neurociencias-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina.ORCID 0009-0002-4208-6351
Giuliana ContinoUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and Instituto de Fisiología, Biología Molecular y Neurociencias-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina.ORCID 0009-0003-9244-4126
Kim Joelle KöhnkeRNA Biology and Molecular Physiology, Faculty of Biology, Bielefeld University, Bielefeld 33615, Germany.ORCID 0009-0001-2810-1538
Marcelo Javier YanovskyFundación Instituto Leloir, Instituto de Investigaciones Bioquímicas de Buenos Aires-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires C1405BWE, Argentina.ORCID 0000-0002-1890-0571
Dorothee StaigerRNA Biology and Molecular Physiology, Faculty of Biology, Bielefeld University, Bielefeld 33615, Germany.ORCID 0000-0002-1341-1381
Julieta Lisa MateosUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and Instituto de Fisiología, Biología Molecular y Neurociencias-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina.ORCID 0000-0002-1156-6662

Funding

Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación (agenciaidiar) PICT-2021-III-A-00071Alexander von Humboldt-Stiftung (AvH) Alumni ProgramConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET) N/ADeutsche Forschungsgemeinschaft (DFG) INST 247/870-1 FUGG
6 · The paper itself

Abstract

Alternative splicing expands proteome diversity and enables phenotypic plasticity across eukaryotes. In plants, mutations in spliceosomal components impair development and stress responses, but the molecular mechanisms remain unclear. Here, we define the molecular function of SPLICING FACTOR 1 (AtSF1) in

Indexed as

ArabidopsisArabidopsis ProteinsCircadian RhythmPlant ImmunityRNA Splice SitesRNA Splicing FactorsAlternative SplicingGene Expression Regulation, PlantMutationProtein BindingArabidopsis ProteinsAt5g51300 protein, ArabidopsisRNA Splice SitesRNA Splicing FactorsArabidopsisbranch pointcircadian clocksplice sitesplicing

Identifiers

PMID42241114
PMCPMC13250555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.