Evidence map›Paper›PMID 42240941›Full record

ReviewTissue engineering and regenerative medicine2026

Harnessing Artificial Intelligence for Regeneration of Endometrium in Asherman's Syndrome.

Gokulnath Anbalagan, Namasivaya Naveen Shanmuga Sundaram, Nandakumar Venkatesan

Abstract readReview
In one paragraph

Review in Tissue engineering and regenerative medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gokulnath AnbalaganFaculty of Biomedical Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.ORCID http://orcid.org/0009-0006-6240-8572
Namasivaya Naveen Shanmuga SundaramDepartment of Computer Science and Medical Engineering, Sri Ramachandra Faculty of Engineering and Technology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.ORCID http://orcid.org/0000-0001-8894-9162
Nandakumar VenkatesanDepartment of Computer Science and Medical Engineering, Sri Ramachandra Faculty of Engineering and Technology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India. nandooniran@gmail.com.ORCID http://orcid.org/0000-0002-2073-9887

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsherman's Syndrome or intrauterine adhesions develop due to acquired endometrium damage, resulting in partial to complete dysfunction of the endometrium within the uterine cavity. The pathophysiology of these adhesions is not clear. Still, the widely accepted mechanism for the development of these adhesions is attributed to three different causes: i. iatrogenic or mechanical, including curettage; ii. pathophysiological conditions, including infection, miscarriage, and Müllerian malformations; and iii. idiopathic.

objectiveThis review critically evaluates the different therapeutic strategies used to manage or treat Asherman's syndrome and the various issues associated with each treatment.

methodsA thorough literature review was performed for other types of polymers currently used or tested for the regeneration of endometrium both clinically and preclinically, and the issues associated with each of the polymers are also discussed.

resultsFinally, we conclude the manuscript by exploring Artificial Intelligence's role in predicting, classifying, and identifying intrauterine adhesions, including machine learning and deep learning algorithms. We also discuss the role of AI in improving biomaterial properties, enhancing stem cell viability, and refining AI-driven diagnostic and therapeutic strategies for better clinical outcomes.

conclusionIn alignment with the United Nations Sustainable Development Goal 4 (Quality Education), this review aims to promote advanced interdisciplinary learning by integrating biomedical engineering, materials science, and artificial intelligence to educate and empower future researchers in regenerative medicine.

Indexed as

Artificial IntelligenceEndometriumGynatresiaRegenerationAnimalsBiocompatible MaterialsFemaleHumansPolymersBiocompatible MaterialsPolymersArtificial intelligenceBiomaterialsDeep learningEndometrial regenerationIntrauterine adhesionsMachine learningReproductive healthSDG 4 (quality education)Stem cells

Identifiers

PMID42240941
PMCPMC13415714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.